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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mr
Alun
Meggy
dementiaresearch@cardiff.ac.uk
Prof
Julie
Williams
williamsj@cardiff.ac.uk
Other degenerative diseases of the nervous system
This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.
Alzheimer’s disease is a common debilitating disorder, which affects individuals, families and communities. Just
under half a million people have Alzheimer’s disease (AD) in the UK with an estimated cost to the economy of £24
billion per year. It is also estimated that the number of people with AD will double in the next generation. It is vital we
understand what causes this disease and develop therapies to prevent, delay and treat it. Finding genes which affect
the development of AD is an important means of pinpointing processes that are going wrong and contributing to the
death of brain cells, which characterises this disease and underlies the symptoms of memory loss and general
cognitive degeneration.
This research is focused on understanding more about how genes are involved in the cause and progression of earlyonset
Alzheimer’s disease (sometimes called young-onset Alzheimer’s disease). We are inviting individuals who first
experienced the onset of symptoms of Alzheimer’s disease before the age of 70 to help with this research.
Participants can be of any age currently.
This is an observational study that involves a Participant interview lasting approximately an hour, donation of a 38ml
blood sample and an interview with a Study Partner also lasting around an hour to an hour and a half.
This study is funded by the Medical Research Council. Around 2000 participants from 75 study centres across the UK
will take part in this research.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Case-controlled study;
You can take part if:
You may not be able to take part if:
1 Acute manic or depressive episode of bipolar disorder 2 Current diagnosis of substance abuse or substance dependence 3 Overall Clinical Dementia Rating scale score of 0 or Global Deterioration Scale score of 1) 4 Blood borne viral infection (such as HIV/AIDS, Hepatitis B,C or D) excludes participants from donating a blood sample. In this instance a saliva sample will be obtained.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by Cardiff University and funded by Medical Research Council (MRC) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 38660
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
