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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mrs
Jayne
Starrett
jayne.starrett@ouh.nhs.uk
Prof
Rajesh
Thakker
rajesh.thakker@ndm.ox.ac.uk
Jayne
Starrett
jayne.starrett@nihr.ac.uk
Metabolic disorders
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Endocrine and metabolic disorders are common and may be caused by hormone excess,
which may be associated with endocrine tumours, or hormone deficiency, that may be due to a congenital abnormality or autoimmune destruction of the gland. These disorders usually occur as non-familial (i.e. sporadic) disorders but they may also occur as part of complex familial syndromic diseases, which may be inherited as autosomal or X-linked traits. The biology of these endocrine and metabolic disorders is poorly understood, but the occurrence of hereditary forms in more than 10% of patients indicates the involvement of genetic abnormalities. The aim of this study is to identify the genetic abnormalities that cause endocrine and metabolic disorders, as this will help to: 1) identify new genetic causes of endocrine and metabolic disorders; 2) establish cellular models that will elucidate the roles of these genes and their encoded proteins in biochemical and physiological pathways; and 3) establish genotype-phenotype correlation and biomarkers for clinical utility.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Cohort study;
You can take part if:
You may not be able to take part if:
The are no exclusion criteria.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Jayne
Starrett
jayne.starrett@nihr.ac.uk
Prof
Rajesh
Thakker
rajesh.thakker@ndm.ox.ac.uk
Mrs
Jayne
Starrett
jayne.starrett@ouh.nhs.uk
The study is sponsored by University of Oxford and funded by European Commission; Medical Research Council (MRC); Wellcome Trust; NIHR Rare Diseases Translational Research Collaboration; .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 35558
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
