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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Prof
Gordon
Proctor
gordon.proctor@kcl.ac.uk
Prof
Gordon
Proctor
gordon.proctor@kcl.ac.uk
Diseases of oral cavity, salivary glands and jawsInflammatory polyarthropathiesExtrapyramidal and movement disordersBullous disordersDiabetes mellitus
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Saliva is formed from contributions of the salivary glands and serum exudates principally from the gingival margins or damaged mucosa and components derived from the environment including a community of microorganisms - the microbiome. Similarly, the gut has a microbiome and this can be assessed by analysing samples of faeces. Various oral and systemic diseases are associated with disturbances in the gut and oral microbiomes. This study aims to examine how the salivary microbiome differs in a range of subjects with and without oral and systemic diseases in order to determine its utility as a biomarker of disease. Secondly the study will determine how the composition of the gut microbiome is influenced by that of the oral (salivary+plaque) microbiome. The study will utilize new methods which allow the composition of microbiomes to be examined in great depth, determine the types and functions of microorganisms in saliva, dental plaque and faeces.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
Subject is pregnant as determined during patient enrolment onto study. Subject has administered antibiotic therapy in the past 3 months.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by King's College London and funded by VERSUS ARTHRITIS .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 34869
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