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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mrs
Fiona
Stirling
fiona.stirling@manchester.ac.uk
Prof
Ian
Bruce
ian.bruce@manchester.ac.uk
Systemic connective tissue disorders
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Connective tissue diseases are an important family of conditions characterised by their multi-system nature. They can affect many organ systems including the joints, skin, kidneys, lungs and blood vessels. Traditionally, CTDs are grouped according to their clinical features for example, systemic lupus erythematosus, systemic sclerosis and myositis. A large number of patients however do not "fit" into these categories and are often described as undifferentiated connective tissue disease (UCTD). These patients have features that overlap with some of the more recognised syndromes, but such patients are currently excluded from studies and trials. Despite this, these patients are likely to give us vital clues to the common features of the whole CTD family. We aim to reconsider how we assess and classify patients with connective tissue disease according to the genes and inflammatory proteins which drive the process, rather than simply on their clinical diagnosis. We will assess patients with CTDs from Greater Manchester to determine common features of their inflammation and blood vessel health. This is important as such patients are rarely studied in such a systematic fashion. The study will help us administer therapies more effectively and aid the design of future therapeutic trials.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Cohort study;
You can take part if:
You may not be able to take part if:
- Males or females under 16 or over 70 - Unwilling to provide informed consent
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by University of Manchester and funded by NIHR Manchester Musculoskeletal Biomedical Research Unit .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 15650
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
