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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mr
Fouad
Noor
fouad@thinksono.com
Mr
Christopher
Deane
advent@nhsbt.nhs.uk
Dr
Nicola
Curry
nicola.curry@ouh.nhs.uk
Deep vein thrombosis
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Deep vein thrombosis (DVT) is a term that describes blood clots (thrombi) that can form in the deep veins. The deep leg veins are commonly affected (such as the proximal veins: the femoral vein or the popliteal vein) or the deep veins of the pelvis. The standard approach to making a diagnosis involves an algorithm combining pre-test probability, a blood test called the D-dimer test, and the patient undergoing an ultrasound of the leg veins. Ultrasound is currently completed by a trained expert (e.g. sonographer or radiologist).
However, handheld ultrasound probes have recently become available and they have enabled ‘app-based’ ultrasonography to be performed. ThinkSono has developed software (AutoDVT software) which it is hoped has the same accuracy for diagnosing DVT as the standard ultrasound. If this study has a positive outcome, it would mean that DVT could be diagnosed at the point of care by non-experts such as nurses, junior doctors, general practitioners and other healthcare staff. By diagnosing DVT early in the clinical pathway (for example, at GP practices), the technology could reduce emergency department admissions and free up specialists to focus on other clinical tasks. These improvements could also potentially reduce the financial burden of the DVT diagnostic service on the NHS.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34526639/ (added 14/12/2021)2025 Other publications in https://pubmed.ncbi.nlm.nih.gov/40025255/ (added 27/05/2025)
You can take part if:
You may not be able to take part if:
1. Pregnant women at 12 weeks or more gestation2. A d-dimer cannot be performed (e.g. due to prior anticoagulation)3. The participant is found to have a distal DVT during the US scan (retrospective exclusion)4. The participant has had a previous radiologically confirmed DVT in the symptomatic leg
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Mr
Fouad
Noor
fouad@thinksono.com
Mr
Christopher
Deane
advent@nhsbt.nhs.uk
Dr
Nicola
Curry
nicola.curry@ouh.nhs.uk
The study is sponsored by Oxford University Hospitals NHS Trust and funded by Wellcome Trust.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 49867
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
