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Be Part of Research - Trial Details - Single-Cell Sequencing Analysis of Radiation Pneumonitis Signals In Patients Treated For Cancer With Radiotherapy

Single-Cell Sequencing Analysis of Radiation Pneumonitis Signals In Patients Treated For Cancer With Radiotherapy

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Pneumonia
Radiation Pneumonitis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Patients with signs of radiation induced lung inflammation, who are referred for a clinical bronchoscopy for investigation, will have a sample sent for single cell sequencing. This is a novel technique which allows for identification of which cells are present and what they are doing. This hopes to better understand radiation pneumonitis, a dose-limiting toxicity in cancer treatment which can be highly morbid and even fatal.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2024 Dec 2025

OBSERVATIONAL

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : Sequencing of all viable single cells present in deep bronchial brushings using transcriptomics to identify what cells are present and what they are doing.

Intervention Arm Group : Bronchoscopy under ELFMAN;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Edinburgh Cancer Centre
    Edinburgh
    EH4 2XU
  • Centre for Information Research, University of Edinburgh
    Edinburgh
    EH16 4UU
  • Henderson Lab
    Edinburgh
    EH16 4UU


The study is sponsored by NHS Lothian




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Read full details for Trial ID: NCT06557343
Last updated 04 February 2025

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