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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559
LillyTrials@Lilly.com


Physicians interested in becoming principal investigators please contact clinical_inquiry_hub@lilly.com


Study Location:

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Be Part of Research - Trial Details - A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Recruiting

Open to: ALL

Age: 12.0 - 17.0

Medical Conditions

Obesity
Weight Gain


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The goal of the study is to assess how tirzepatide impacts bodyweight and cardiovascular risk factors when used in conjunction with healthy nutrition and physical activity in adolescents with obesity and multiple weight related comorbidities. The study will last approximately 76 weeks and may include up to 23 visits.

Participants who have completed the primary 72-week GPIX study and have been off treatment for no more than 12 weeks (including the 4-week safety follow-up period), will have the opportunity to receive an additional 156 weeks of treatment with tirzepatide as well as continuing the lifestyle intervention.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2024 Oct 2027

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered SC

Intervention Arm Group : Tirzepatide;

Intervention Type : DRUG
Intervention Description : Administered SC

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Leeds General Infirmary
    Leeds
    LS1 3EX
  • Southampton General Hospital
    Southampton
    SO16 6YD
  • Leicester Royal Infirmary
    Leicester
    LE1 5WW
  • Sheffield Children's Hospital
    Sheffield
    S10 2TH
  • Alder Hey Children's Hospital
    Liverpool
    L14 5AB
  • Addenbrooke's Hospital
    Cambridge
    CB2 0SL
  • Royal Hospital for Children
    Glagow
    G51 4TF
  • Paediatric and Adolescent OutpatientsElizabeth Garrett Anderson WingUniversity College Hospital
    London
    WC1E 6DB
  • Royal Victoria Infirmary
    Newcastle upon Tyne
    NE1 4PL

Physicians interested in becoming principal investigators please contact clinical_inquiry_hub@lilly.com


Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559
LillyTrials@Lilly.com



The study is sponsored by Eli Lilly and Company




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Read full details for Trial ID: NCT06439277
Last updated 22 March 2026

This page is to help you find out about a research study and if you may be able to take part

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