Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Claudia Schulte +4915222801491
claudia.schulte@biotest.com


Iris Bobenhausen, PhD +4915222801073
iris.bobenhausen@biotest.com


Study Location:

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Be Part of Research - Trial Details - Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Pneumonia


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The main objective of the trial is to assess the efficacy and safety of trimodulin as adjunctive treatment to standard of care (SoC) compared to placebo plus SoC in adult hospitalized subjects with sCAP on invasive mechanical ventilation (IMV).

Other objectives are to determine detailed pharmacokinetic (PK) properties of trimodulin in a PK substudy and to determine its pharmacodynamic (PD) properties.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Sep 2023 Oct 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : IMP will be administered via IV infusion on 5 consecutive days

Intervention Arm Group : Trimodulin;

Intervention Type : DRUG
Intervention Description : IMP will be administered via IV infusion on 5 consecutive days

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • St Thomas' Hospital
    London
    SE1 7EH
  • Royal Surrey County Hospital
    Guildford
    GU2 7XX
  • Queen Elizabeth University Campus
    Glasgow
    G11 6NT
  • Derriford Hospital
    Plymouth
    PL6 8DH


The study is sponsored by Biotest




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Read full details for Trial ID: NCT05722938
Last updated 05 May 2025

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