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Be Part of Research - Trial Details - Efficacy and Safety Study of HRO350 in Patients With Mild-to-moderate Psoriasis (the 'HeROPA' Study).

Efficacy and Safety Study of HRO350 in Patients With Mild-to-moderate Psoriasis (the 'HeROPA' Study).

Medical Conditions

Psoriasis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


HRO350 contains an oil-based extract from herring roe (Clupea harengus) in soft capsules and contains phospholipids (complex lipids) which are naturally rich in marine polyunsaturated fatty acids. All the lipids in HRO350 are natural components of the human diet. It is not fully known how HRO350 exerts its effects, however there are indications that it might have a modulatory effect on the inflammatory processes involved in causing psoriasis. The study is a randomised, double-blind, placebo controlled, dose finding, multi-centre, phase 2B study. Approximately 519 patients will be participating in the UK, Norway, Germany, Finland and Poland. Patients will receive either 1050mg or 2100mg HRO0350 daily, or placebo for up to 52 weeks and will be followed up for a further 8 weeks.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

May 2023 Feb 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Active substance phospholipid esters from herring roe oil (PEHeRo)

Intervention Arm Group : 1050 mg HRO350;2100 mg HRO350;

Intervention Type : DRUG
Intervention Description : Placebo; as a sunflower oil in capsules similar to the interventional drug product HRO350 in terms of appearance, smell and taste.

Intervention Arm Group : 1050 mg HRO350;Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Salford Royal Hospital
    Salford
  • University Hospital of North Durham
    Durham
  • Kiltearn Medical Centre
    Nantwich
  • St Luke's Hospital
    Bradford
  • University Hospitals Dorset
    Poole
  • Luton and Dunstable University Hospital
    Luton
  • Rowden Surgery
    Chippenham
  • Honiton Surgery
    Honiton
  • Trowbridge Health Centre
    Trowbridge
  • Kings Mill Hospital
    Sutton in Ashfield
  • Waterloo Medical Centre
    Blackpool
  • The Practice of Health
    Barry
  • Heart of Bath Medical Partnership
    Bath
  • Concord Medical Centre
    Bristol
  • Royal Primary Care Ashgate
    Chesterfield
  • Hathaway Medical Centre
    Chippenham
  • Lakeside Healthcare Research
    Corby
  • Haven Health
    Felixstowe
  • Sherbourne Medical Practice
    Leamington Spa
  • Oak Tree Surgery
    Liskeard
  • Babylon Healthcare GP at Hand
    London
  • Newquay Health Centre
    Newquay
  • St Clare Medical Centre
    Penzance
  • Clarence House Medical Centre
    Rhyl
  • Grove Surgery
    Thetford
  • West Walk Surgery
    Yate


The study is sponsored by Arctic Bioscience and is in collaboration with Smerud Medical Research International AS.




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Read full details for Trial ID: NCT06125808
Last updated 22 March 2024

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