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Be Part of Research - Trial Details - A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight

Not Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Osteoarthritis, Knee
Sleep Apnea, Obstructive
Obesity
Overweight


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits. Addendum (2) is optional and available to approximately 500 participants to continue treatment with retatrutide for up to an additional 24 weeks.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jul 2023 Apr 2026

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Administered SC

Intervention Arm Group : Retatrutide Dose 1;Retatrutide Dose 2;Retatrutide Dose 3;Retatrutide Extension Period;

Intervention Type : DRUG
Intervention Description : Administered SC

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Heartlands Hospital
    Birmingham
    B9 5SS
  • Aintree University Hospital NHS Foundation Trust
    Liverpool
    L9 7AL
  • Leicester General Hospital
    Leicester
    Leicestershire
    LE5 4PW
  • Panthera Biopartners - North London
    Enfield
    London, City Of
    EN3 4GS
  • Panthera Biopartners - Sheffield
    Sheffield
    S2 5FX
  • Glasgow Royal Infirmary
    Glasgow
    Scotland
    G31 2ER
  • Layton Medical Centre
    Blackpool
    Lancashire
    FY3 7EN
  • Rowden Surgery
    Chippenham
    England
    SN15 2SB
  • St Clare Medical Centre
    Penzance
    TR18 3DX


The study is sponsored by Eli Lilly and Company





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Read full details for Trial ID: NCT05929066
Last updated 23 January 2025

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