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Be Part of Research - Trial Details - Xanamem® in Adults with Major Depressive Disorder and Impaired Cognition (XanaCIDD)

Xanamem® in Adults with Major Depressive Disorder and Impaired Cognition (XanaCIDD)

Completed

Open to: ALL

Age: 18.0 - 75.0

Medical Conditions

Depressive Disorder
Depression
Cognitive Dysfunction
Depressive Disorder, Major


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Xanamem is being developed as a potential treatment for symptomatic, early stages of Alzheimer's Disease (AD) and Major Depressive Disorder (MDD).

This XanaCIDD Phase II study in MDD is to investigate the safety and efficacy of Xanamem™ in treating patients with cognitive and depressive symptoms. Trial participants will be randomized to either receive 10mg of Xanamem™ once daily or a Placebo at a 1:1 ratio in a double-blinded fashion.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Nov 2022 Jul 2024

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Xanamem™ is formulated in green and cream-colored size 3, Coni-Snap-shaped gelatin capsules as an excipient blend at a dose of 10mg. It contains the active pharmaceutical ingredient of UE2343.

Intervention Arm Group : 10 mg Xanamem™;

Intervention Type : DRUG
Intervention Description : Matching placebo which is identical in appearance to the test product (10 mg Xanamem™ QD) except that it contains no active ingredient.

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • MAC Clinical Research - Manchester
    Manchester
    M13 9NQ
  • St Pancras Clinical Research
    London
    EC2Y 8EA
  • Glasgow Memory Clinic
    Motherwell
    ML1 4UF
  • Clerkenwell Health
    London
    W1G 8DR
  • MAC Clinical Research - South Yorkshire
    Tankersley
    S75 3DL


The study is sponsored by Actinogen Medical and is in collaboration with AXIOM Real Time Metrics.




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Read full details for Trial ID: NCT05657691
Last updated 20 January 2025

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