We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Gerome
Breen
GLADstudy@kcl.ac.uk
Saakshi
Kakar
GLADstudy@kcl.ac.uk
Laura
Meldrum
GLADstudy@kcl.ac.uk
Iona
Smith
GLADstudy@kcl.ac.uk
Mood [affective] disordersNeurotic, stress-related and somatoform disorders
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Depression and anxiety disorders are the most common psychiatric disorders worldwide, affecting at least 30% of the
population over their lifespan and are highly correlated, both phenotypically and genetically. There is an acute need to
understand the causes of depression and anxiety and to develop new treatments. These disorders can be debilitating,
affecting all aspects of an individual’s life. However, efforts to understand the aetiology of these disorders requires very
large sample sizes, which are not currently available. Moreover, the UK lacks a large platform that can enable
experimental medicine studies of depression and anxiety nationally. Therefore, the development of a research
resource comprised of individuals who have suffered a lifetime occurrence of anxiety or depression will give
researchers access to a large population based sample. This will facilitate analysis to inform our understanding of
both anxiety and depressive disorders.
The aim of this project is to lead on such studies by first recruiting a large number of participants who will provide
responses to a comprehensive set of questions. The participants will be recruited into an existing biobank, the NIHR
BioResource for Translational Research in Common and Rare Diseases, a recontactable biobank. Our recruitment
will help towards forming the largest recontactable biobank of participants diagnosed with or suffering from two very
common disorders, depression and anxiety, who will be primarily recruited through an online platform. Our project will
explore genetic and environmental factors associated with risk for depression and anxiety disorders in the UK, to
understand these common disorders and help develop better treatments.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Genetic epidemiology;
You can take part if:
You may not be able to take part if:
Individuals without the capacity to provide informed consent Individuals under the age of 16 years Individuals who do not have a current diagnosis of who do not meet the screening criteria for a lifetime DSM-5 diagnosis of depression or anxiety
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Gerome
Breen
GLADstudy@kcl.ac.uk
Laura
Meldrum
GLADstudy@kcl.ac.uk
Iona
Smith
GLADstudy@kcl.ac.uk
Saakshi
Kakar
GLADstudy@kcl.ac.uk
The study is sponsored by King's College London and funded by Medical Research Council (MRC); NIHR Maudsley Biomedical Research Centre; FONDATION PETERS; .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 40136
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
