Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Aygul Dagbasi
+44 7708369942
a.dagbasi16@imperial.ac.uk


Prof Gary Frost
+44 (0)20 7594 0959
g.frost@imperial.ac.uk


Mrs Monica Hill
+44 7340626852
m.mischie18@imperial.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - Pilot clinical trial on using health and dietary monitoring technologies to prevent diet-related diseases

Pilot clinical trial on using health and dietary monitoring technologies to prevent diet-related diseases

Not Recruiting

Open to: All Genders

Age: Adult

Medical Conditions

Healthy individuals at risk of developing non-communicable diseases (heart disease, type 2 diabetes, cancer).


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Unhealthy diets are associated with metabolic changes and increased risk of non-communicable diseases (NCDs). However, current understanding of the relationship between diet and the development of NCD is limited by a number of factors. These include a lack of understanding of dietary mechanisms that drive NCD, inaccurate tools to collect dietary information, a nascent understanding of the role of personalised nutrition, and the lack of data in vulnerable groups where NCDs are often over-represented.

The relationship between dietary intake and the development of NCD is complex. The understanding of how diet relates to the development of metabolic risk factors on a background of non-modifiable risk factors is improving with the greater understanding of the metabolic pathways that are responsive to dietary profile and lead to change in NCD risk. Tools that profile the genome, metabolome, epigenome, microbiome, and inflammation are key to understanding the impact of diet on NCDs. However, these systems are mostly studied in isolation and their relative importance of how they interact with each other is not understood.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Dec 2023 01 Mar 2024

Participants will need to wear a micro-camera that tracks their dietary intake and a wristband that measures their physical activity and sleeping patterns for seven days each on three separate occasions. In addition, while the volunteers are wearing the camera and the wristband, they will need to complete a five-day food diary online. At the end of the first and third period of wearing the devices and completing the food diaries, the volunteers will be asked to attend two studies, where they will have their body composition and general health assessed, provide blood, stool, breath, and urine samples. In addition, during these two study visits and only at the Imperial College London site, the volunteers will be asked to undergo a mixed meal tolerance test where the participants will consume a standard meal and then have blood samples taken over a six hours period.
At the end of the second period of wearing the devices and completing the food diaries, the volunteers will be asked to attend a 30-minutes study visit where they will only have their body composition and general health assessed (no biofluids will be taken). After the volunteers have completed all study visits, they will be asked to complete short questionnaires through which they will be able to express their views on participating in the study.


Healthy volunteers (male and female), aged 18-65 years old, with BMI over 25 kg/m² and two other risk factors.

You can take part if:



You may not be able to take part if:


1. Suffer from the following conditions: type 2 diabetes, chronic gastrointestinal conditions (Crohn’s disease, irritable bowel syndrome, ulcerative colitis etc.), acute infectious diseases, cardiovascular diseases, hypertension, autoimmune conditions, 2. Were on antibiotic treatment in the 12 weeks preceding enrolment of the clinical trial, 3. Pregnant or currently breastfeeding, 4. Are currently participating in other clinical trials or participated in another trial within the last 12 weeks, 5. Require any medical interventions during the study period, 6. Cannot give consent by yourself.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • NIHR Imperial Clinical Research Facility
    Hammersmith Hospital Du Cane Rd Shepherd's Bush
    London
    W12 0HS
  • Atlantia Clinical Trials
    Heron House Offices First Floor Blackpool
    Cork
    T23 R50R
  • Laboratory of Forensic Medicine and Toxicology
    School of Medicine Aristotle University Thessaloniki
    Thessaloniki
    54124
  • CIC bioGUNE, Precision Medicine and Metabolism Lab
    Bizkaia Science and Technology Park bld 801 A
    Derio, Bizkaia
    48160
  • Faculty of Medicine and Dentistry. University of Valencia UVEG-CIBEROBN
    Avda. Blasco Ibañez, nº 15
    Valencia
    46010

Participants will receive £200 upon completion of the study to reimburse them for the time they have taken to attend study visits.
No risks

Mrs Monica Hill
+44 7340626852
m.mischie18@imperial.ac.uk


Dr Aygul Dagbasi
+44 7708369942
a.dagbasi16@imperial.ac.uk


Prof Gary Frost
+44 (0)20 7594 0959
g.frost@imperial.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by Imperial College London and funded by UK Research and Innovation; European Union Horizon Programme.




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Read full details for Trial ID: ISRCTN11564218

Or CPMS 59206

Last updated 03 April 2024

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