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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk


Angus Williams
angus.williams@cntw.nhs.uk


Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk


Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk


Study Location:

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Be Part of Research - Trial Details - VISION-QUEST

VISION-QUEST

Medical Conditions

Schizophrenia, schizotypal and delusional disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


One in three people with psychosis experience distressing visual hallucinations (VH) – seeing things that others cannot. When VH occur, they can have a detrimental impact on people’s lives, such as more frequent and prolonged hospital admissions, and greater likelihood of suicide.

A previous study by this team (The experience of VH in psychosis from the first-person perspective: IRAS ID: 291872) spoke to 12 people with VH. We found that the way in which people make sense of their VH are one of the keys factors driving distress. For example, when people thought VH were negative or threatening, they found them to be more distressing and this had a bigger impact on their lives. The next step is therefore to explore this on a larger scale to understand more about people’s appraisals of VH. Then this can be used to validate a scale of VH appraisals and develop targeted treatments for these.

To do so, this study will develop a questionnaire focused on people’s beliefs about VH. It will also explore the relationship of visions to other potential casual mechanisms such as poor sleep, and excessive worry.

900 people with psychosis will complete self-report questionnaires (approximately 30-45 minutes). After this, a subgroup of 100 participants will be asked to repeat some of the measures a week later to test if the appraisals measure is consistent.
We will recruit participants via the Clinical Research Network (CRN), which has research staff based in NHS Trusts nationwide. The study is funded by the National Institute of Health Research. Recruiting via the CRN is a method which has been successfully used by other research group, with minimal risks identified.

By developing a new measure and our knowledge of causal mechanisms of visions, it will be the next important steps to developing better treatments for these.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

04 Mar 2024 31 Mar 2026

Observational

Observational type: Cross-sectional;



You can take part if:



You may not be able to take part if:


- Insufficient English language to understand and complete questionnaires. - Visions as a result of organic disorders, brain injury or ONLY when under the influence of alcohol or substances.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Charlton Lane Site
    Charlton Lane
    Cheltenham
    Gloucestershire
    GL53 9DZ
  • Science And Technology Centre
    University Of Reading
    whiteknights
    Reading
    Berkshire
    RG6 6BZ
  • Leicestershire Partnership NHS Trust Mental Health Services
    George Hine House
    gipsy Lane
    humberstone
    Leicester
    Leicestershire
    LE5 0TD
  • Maudsley Hospital
    Denmark Hill
    London
    Greater London
    SE5 8AZ
  • St Margaret's Hospital
    The Plain
    Epping
    Essex
    CM16 6TN
  • Cambridgeshire And Peterborough Mental Health Partnership Tr Hq
    Elizabeth House, Fulbourn Hospital
    cambridge Road
    fulbourn
    Cambridge
    Cambridgeshire
    CB21 5EF
  • Trust Headquarters
    Swandean Hospital
    arundel Road
    Worthing
    West Sussex
    BN13 3EP
  • St Nicholas Hospital (newcastle Upon Tyne)
    Jubilee Road, Gosforth
    Newcastle Upon Tyne
    Tyne And Wear
    NE3 3XT
  • St Mary's Health Campus
    Milton Road
    Portsmouth
    Hampshire
    PO3 6AD
  • Ravenswood House
    Knowle
    Fareham
    Hampshire
    PO17 5NA
  • Gmw Trust Headquarters
    Prestwich Site
    bury New Road
    prestwich
    Manchester
    Greater Manchester
    M25 3BL
  • HULL WEST CMHT
    RV9FK@2.16.840.1.113883.2.1.3.2.4.18.48
  • Tees, Esk, Wear Valley NHS Trust (durham)
    Trust Headquarters
    west Park Hospital
    edward Pease Way
    Darlington
    County Durham
    DL2 2TS
  • Whiteleaf Centre
    Bierton Road
    Aylesbury
    Buckinghamshire
    HP20 1EG
  • Trust Head Office
    99 Waverley Road
    St. Albans
    Hertfordshire
    AL3 5TL
  • LADYWELL UNIT
    RV509@2.16.840.1.113883.2.1.3.2.4.18.48
  • BETHLEM ROYAL HOSPITAL
    Y7O8M@2.16.840.1.113883.2.1.3.2.4.18.48
  • THE LAMBETH HOSPITAL
    H2H5N@2.16.840.1.113883.2.1.3.2.4.18.48

Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk


Angus Williams
angus.williams@cntw.nhs.uk


Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk


Dr Charlotte Aynsworth
charlotte.aynsworth@cntw.nhs.uk



The study is sponsored by CUMBRIA, NORTHUMBERLAND, TYNE AND WEAR NHS FOUNDATION TRUST and funded by NIHR Academy .




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for Trial ID: CPMS 58033

Last updated 09 April 2026

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