Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Prof Catherine Smith
catherine.smith@kcl.ac.uk


Prakash Patel
prakash.patel@kcl.ac.uk


Study Location:

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Be Part of Research - Trial Details - PLUM

PLUM

Medical Conditions

Papulosquamous disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Pustular forms of psoriasis are characterised by painful, intensly inflamed, red skin studded with sterile pustules. The disease may be chronic and localised, typically to the hands and feet, or, more rarely, more generalised across the body and potentially life-threatening. Although pustular psoriasis accounts for less than 10% of psoriasis cases it consistently ranks highest among all variants in terms of symptoms and functional impairment. There is recent evidence, including work from our own group, to suggest that distinct underlying genetic and molecular pathways found in patients with pustular disease could be responsible for this particular disease presentation. The poor response to therapies used to great effect in other types of psoriasis may also be expla

In PLUM we aim to identify and understand the genes that may have an influence on the development of pustular psoriasis, related immune pathways and responses to treatment. We will recruit patients, disease controls, healthy volunteers and relations of patients and invite them to donate blood samples, and optional skin and hair pluck samples.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

15 Mar 2017 31 Dec 2026

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


1. Individuals unable to give written informed consent 2. Individuals who have received a blood transfusion within 4 weeks 3. Individuals who are known to be infected with HIV, HBV or other blood-borne viruses


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Cardiff & Vale University Lhb
    Woodland House
    maes-y-coed Road
    Cardiff
    CF14 4HH
  • Guy's Hospital
    Great Maze Pond
    London
    Greater London
    SE1 9RT
  • Ninewells Hospital
    Ninewells Avenue
    Dundee
    Angus
    DD1 9SY
  • Norfolk & Norwich University Hospital
    Colney Lane
    colney
    Norwich
    Norfolk
    NR4 7UY
  • Royal Free Hospital
    Pond Street
    London
    Greater London
    NW3 2QG
  • Salford Royal
    Stott Lane
    Salford
    Greater Manchester
    M6 8HD
  • Addenbrooke's Hospital
    Hills Road
    Cambridge
    Cambridgeshire
    CB2 0QQ
  • Basildon Hospital
    Nethermayne
    Basildon
    Essex
    SS16 5NL
  • Royal Liverpool University Hospital
    Prescot Street
    Liverpool
    Merseyside
    L7 8XP
  • St Lukes Hospital
    Little Horton Lane
    Bradford
    West Yorkshire
    BD5 0NA
  • University Hospital Of North Durham
    North Road
    Durham
    County Durham
    DH1 5TW
  • Mid Essex Hospital
    Broomfield Hospital
    Chelmsford
    Essex
    CM1 7ET
  • St Albans City Hospital
    Waverley Road
    St. Albans
    Hertfordshire
    AL3 5PN
  • Hemel Hempstead Hospital
    Hillfield Road
    Hemel Hempstead
    Hertfordshire
    HP2 4AD
  • Northern Care Alliance NHS Foundation Trust
    Salford Royal
    stott Lane
    Salford
    Greater Manchester
    M6 8HD
  • The Dudley Group NHS Foundation Trust
    Russells Hall Hospital
    pensnett Road
    Dudley
    DY1 2HQ
  • West Glasgow Ambulatory Care Hospital
    Dalnair Street
    yorkhill
    Glasgow
    G3 8SJ
  • Watford General Hospital
    Vicarage Road
    Watford
    Hertfordshire
    WD18 0HB
  • St Mary's Hospital
    West Wing
    milton Road
    Portsmouth
    Hampshire
    PO3 6AD

Prakash Patel
prakash.patel@kcl.ac.uk


Prof Catherine Smith
catherine.smith@kcl.ac.uk



The study is sponsored by GUY'S AND ST THOMAS' NHS FOUNDATION TRUST and funded by NIHR Evaluation, Trials and Studies Co-ordinating Centre (NETSCC) .




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for Trial ID: CPMS 33029

Last updated 21 November 2024

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