We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Joshua
Haynes
joshua.haynes@manchester.ac.uk
Paul
Warren
paul.warren@manchester.ac.uk
Paul
Warren
paul.warren@manchester.ac.uk
Neurotic, stress-related and somatoform disordersSymptoms and signs involving cognition, perception, emotional state and behaviour
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Functional Neurological Disorder (FND) is a debilitating condition often causing problems with dizziness. While very common, it is little understood and treatment options are limited. We will study FND from a new perspective testing the idea that dizziness symptoms in FND might arise from problems with the brain systems that help us to estimate both our own movement and that of other things in the environment while we are moving.
In this 3-year study we will focus on a subgroup of FND patients with Persistent Postural-Perceptual Dizziness (3PD), who experience particularly pronounced symptoms. Patient participants will be recruited primarily from four NHS sites (Manchester - 2 sites; London - 1 site; Edinburgh - 1site) across the UK with established balance/vestibular/ENT clinics. All experimental work will be carried out at the University of Manchester in the Perception and Virtual Reality (VR) laboratories of Chief Investigator Dr. Paul Warren.
Both patient participants (with a 3PD diagnosis) and age- and IQ-matched control participants will take part in a series of experiments in which they make judgements over many trials about either their own movement or that of something else in the environment, under different viewing conditions. Sometimes movement will be active (i.e. under their own steam) and sometimes passive (i.e. using a motion platform device to carefully control their movement). From these data we will be able to estimate how the ability to interpret different sources of sensory information about movement change in 3PD, as well as how this might predict 3PD symptoms. In the final part of the study we will use our findings to undertake a preliminary investigation of VR-based therapies designed to reduce 3PD symptoms. We anticipate that our research will lead to a significantly improved understanding of the causes of dizziness in 3PD/FND and more targeted and effective therapies.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
Participants (3PD or Control) will be excluded if they have any additional diagnosed cardiac, neurological, ophthalmological, psychiatric or other relevant condition.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Paul
Warren
paul.warren@manchester.ac.uk
Joshua
Haynes
joshua.haynes@manchester.ac.uk
Paul
Warren
paul.warren@manchester.ac.uk
The study is sponsored by University of Manchester and funded by Medical Research Council (MRC) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 59570
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
