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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Matt
Reed
+44 (0)131 242 3863
matthew.reed@nhslothian.scot.nhs.uk
Mrs
Lynn
Dinsmore
-
lynn.dinsmore@ed.ac.uk
Mrs
Lynn
Dinsmore
-
ASPIRED.study@ed.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
Early diagnosis of patients presenting to Emergency Departments with undiagnosed syncope (blackouts).
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Syncope (sudden loss of consciousness also known as blackout or fainting) causes over 600,000 people to visit emergency departments every year in the UK. Often, by the time the patient is seen by the medical team they have fully recovered making it hard to diagnose the underlying problem. A mobile heart ECG monitoring device has recently been developed (BodyGuardian Mini; Preventice Solutions). This device can record the patient’s heartbeat and heart electrical rhythm tracing for up to 14 days. By wearing the mobile heart monitor after attendance at the Emergency Department there may be a better chance of finding an underlying problem that caused the blackout. This study aims to recruit people who, after investigation at the Emergency Department a cause hasn’t been found for their episode of blackout. The goal is to discover if by providing patients with a 14-day mobile heart ECG monitor, doctors can better diagnose and treat the cause of a sudden loss of consciousness and reduce the number of further episodes and their potential serious consequences (i.e. injury, anxiety, poor quality of life and on rare occasions, death), reduce hospital admissions, reduce overall health costs and increase quality of life. At the moment it is not known how long patients who have this type of monitor should be monitored for, so this study will also answer this question.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36822806/ (added 24/02/2023)
You can take part if:
You may not be able to take part if:
1. Obvious underlying cause after assessment:1.1. Features of vasovagal syncope AND absence of structural heart disease AND normal physical examination AND normal ECG1.2. Dysrhythmia on pre-hospital or hospital ECG as likely cause of syncope 1.3. Postural hypotension (symptomatic postural drop >20 mmHg AND suggestive history)1.4. Confirmed diagnosis of Pulmonary Embolus or Acute Myocardial Infarction1.5. Radiological diagnosis or clinical signs/symptoms of cerebrovascular accident/transient ischemic attack or subarachnoid haemorrhage1.6. Evidence of: 1.6.1. Haemorrhage1.6.2. Alcohol or illicit drugs1.6.3. Epileptic seizure1.6.4. Hypoglycemia1.6.5. Head trauma1.6.6. Other obvious cause of syncope as presumptive cause of TLoC2. Inability to consent3. Previous recruitment into the study4. Patient in custody or prison5. Aged <16 years6. Patient does not reside within local health board and will therefore be lost to medical record follow up 7. Five or more self-reported episodes of syncope in the previous 4 weeks
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Mrs
Lynn
Dinsmore
-
lynn.dinsmore@ed.ac.uk
Dr
Matt
Reed
+44 (0)131 242 3863
matthew.reed@nhslothian.scot.nhs.uk
Mrs
Lynn
Dinsmore
-
ASPIRED.study@ed.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by The University of Edinburgh and Lothian Health Board ACCORD and funded by British Heart Foundation.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 52042
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
