Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

UCB Cares 1-844-599-2273 (USA)
UCBCares@ucb.com


UCB Cares 001 844 599 2273
UCBCares@ucb.com


Study Location:

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Be Part of Research - Trial Details - A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)

Recruiting

Open to: ALL

Age: 18.0 - 89.0

Medical Conditions


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The purpose of the study is to evalute the efficacy, safety and tolerability of rozanolixizumab for treatment of adult participants with myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOG-AD).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Feb 2022 May 2027

Publications

"Mader S, Kumpfel T, Meinl E. Pathomechanisms in demyelination and astrocytopathy: autoantibodies to AQP4, MOG, GFAP, GRP78 and beyond. Curr Opin Neurol. 2022 Jun 1;35(3):427-435. doi: 10.1097/WCO.0000000000001052."; "35674086"

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : * Pharmaceutical form: Solution for infusion* Route of administration: subcutaneous infusion

Participants will receive pre-specified doses of rozanolixizumab.

Intervention Arm Group : Rozanolixizumab Arm;

Intervention Type : OTHER
Intervention Description : * Pharmaceutical form: Solution for infusion* Route of administration: subcutaneous infusion

Participants will receive placebo.

Intervention Arm Group : Placebo Arm;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Mog001 40661
    Liverpool
  • Mog001 40163
    Oxford


The study is sponsored by UCB Biopharma SRL




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Read full details for Trial ID: NCT05063162
Last updated 24 April 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.