Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Ulrika Aberg
0046701679744
ulrika.aberg@uu.se


Prof Anna Bill-Axelson


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - SPCG-17 - when to treat men who are in active surveillance for prostate cancer, a randomized study comparing current practice with standardized triggers for initiation of curative treatment

SPCG-17 - when to treat men who are in active surveillance for prostate cancer, a randomized study comparing current practice with standardized triggers for initiation of curative treatment

Medical Conditions

Active surveillance for low-risk and favourable intermediate-risk prostate cancer


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Prostate cancer is the most common cancer in men in the Western world. If prostate cancer is detected when it is at an early stage and not causing any symptoms, treatment is not immediately needed. Instead the patient’s condition is carefully monitored (active surveillance) with blood tests (the PSA test), physical examination of the prostate, and taking a small sample of tissue (a biopsy) from the prostate. There is however a problematic knowledge gap surrounding active surveillance, and the most important piece of evidence missing is when treatment is likely to be needed and beneficial for the patient. Moreover, the optimal follow-up programs are not yet defined. The aim of this study is to compare current practice of active surveillance with a standardised program for follow-up and triggers for treatment. It is believed that standardised criteria for treatment will reduce unnecessary treatment of early stage prostate cancer, without increasing the risk of not being cured in time. Patients can safely be followed-up by nurses, which increase continuity. Standardised, evidence-based active surveillance programs can also decrease inequities of health care in and between countries.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Oct 2016 30 Sep 2024

Publications

2019 Protocol article in http://dx.doi.org/10.1136/bmjopen-2018-027860 protocol (added 21/09/2020)

Participants are randomly allocated to one of two equally sized groups. One group is monitored according to current clinical practice at the clinic where the participant is a patient. The other group is monitored according to a standardised program where treatment is initiated only when specific criteria are fulfilled. Both groups undergo a standard set of prostate biopsies and an MRI examination of the prostate upon inclusion in the study, and are then followed in the same way with PSA testing every 6 months, a yearly clinical check-up, and an MRI examination of the prostate every 2 years. In the clinical practice group, further biopsies and tests can be performed according to the urologist’s judgement.


Scandinavian and British men with untreated low-risk or favourable intermediate-risk prostate cancer, eligible for active surveillance

You can take part if:



You may not be able to take part if:


Participants not fulfilling the inclusion criteria


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Akademiska Hospital
    Uppsala
    SE-752 37
  • Sahlgrenska University Hospital
    Göteborg
    SE-413 45
  • Örebro University Hospital
    Örebro
    SE-701 85
  • Linköping University Hospital
    Linköping
    SE-581 85
  • Helsinki University Hospital
    Helsinki
    FI-00029
  • The Royal Marsden Hospital
    London
    SW3 6JJ
  • King's College Hospital
    London
    SE5 9RS
  • Umeå University Hospital
    Umeå
    SE-901 85
  • Sundsvall Hospital
    Sundsvall
    SE-851 86
  • Sunderby Hospital
    Luleå
    SE-971 80
  • Växjö Hospital
    Växjö
    SE-351 85
  • St Olavs Hospital
    Trondheim
    NO-7006
  • Vestfold Hospital
    Tønsberg
    NO-3116
  • Ålesund Hospital
    Ålesund
    NO-6026
  • Oslo University Hospital
    Oslo
    NO-0424
  • Guy’s Hospital
    London
    SE1 9RT
  • Epsom and St Helier Hospital
    Surrey
    KT18 7EG
  • Seinäjoki Central Hospital
    Tampere
    FI-33014
  • University Hospital of North Norway
    Tromsø
    NO-9038
  • Odense University Hospital
    Odense
    DK-5000
  • Queen Elizabeth Hospital
    Woolwich Stadium Road Woolwich
    London
    SE18 4QH
  • Bedford Hospital
    Kempston Road
    Bedford
    MK42 9DJ
  • Croydon University Hospital
    London Road
    Croydon
    CR7 7YE

Not provided at time of registration

Dr Ulrika Aberg
0046701679744
ulrika.aberg@uu.se


Prof Anna Bill-Axelson



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by Uppsala University and funded by Cancerfonden; Svenska Forskningsrådet Formas; Nordic Cancer Union.





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Read full details for Trial ID: ISRCTN64382660
Last updated 06 December 2024

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