Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Louise Sorensen 0113 343 7764
MRCTarget@leeds.ac.uk


Study Location:

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English | Cymraeg
Be Part of Research - Trial Details - Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

Medical Conditions

Polymyalgia Rheumatica
Giant Cell Arteritis
Arteritis


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


A multi-centre observational study recruiting prospective and retrospective cohorts of patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The primary aim is to find genetic determinants of GCA and PMR susceptibility, in order to yield novel insights into disease pathogenesis. A subset of the retrospective cohort is also enrolled in a post-marketing surveillance registry of patients eligible for, or receiving tocilizumab, to treat their relapsing or refractory GCA.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2005 Mar 2028

OBSERVATIONAL



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Hammersmith Hospital, Imperial College Healthcare NHS Trust
    London
  • Warwick Hospital, South Warwickshire NHS Foundation Trust
    Warwick
  • Nevill Hall Hospital, Aneurin Bevan University Health Board
    Abergavenny
  • Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust
    Aylesbury
  • Barnsley Hospital, Barnsley Hospital NHS Foundation Trust
    Barnsley
  • Basildon University Hospital, Basildon and Thurrock University Hospitals NHS Foundation Trust
    Basildon
  • Basingstoke and North Hampshire Hospital, Hampshire Hospitals NHS Foundation Trust
    Basingstoke
  • Royal National Hospital for Rheumatic Diseases, Royal United Hospitals Bath NHS Foundation Trust
    Bath
  • Birmingham Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust
    Birmingham
  • Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust
    Birmingham
  • Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust
    Bristol
  • Queen's Hospital, University Hospitals of Derby and Burton NHS Foundation Trust
    Burton Upon Trent
  • West Suffolk Hospital, West Suffolk NHS Foundation Trust
    Bury Saint Edmunds
  • Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust
    Cambridge
  • Chelsea and Westminster Hospital, Chelsea and Westminster Hospital NHS Foundation Trust
    Chelsea
  • West Middlesex University Hospital, Chelsea and Westminster Hospital NHS Foundation Trust
    Chelsea
  • Ashford and St Peter's Hospitals, Ashford & St Peter's Hospitals NHS Foundation Trust
    Chertsey
  • Countess of Chester Hospital, Countess of Chester NHS Foundation Trust
    Chester
  • Christchurch Hospital, University Hospitals Dorset NHS Foundation Trust
    Christchurch
  • Croydon University Hospital, Croydon Health Service NHS Trust
    Croydon
  • Darlington Memorial Hospital, County Durham and Darlington NHS Foundation Trust
    Darlington
  • Royal Derby Hospital, University Hospitals of Derby and Burton NHS Foundation Trust
    Derby
  • Doncaster Royal Infirmary, Doncaster and Bassetlaw Hospitals NHS Foundation Trust
    Doncaster
  • Ninewells Hospital and Medical School, NHS Tayside
    Dundee
  • Royal Devon and Exeter Hospital, Royal Devon and Exeter NHS Foundation Trust
    Exeter
  • Frimley Park Hospital, Frimley Park Hospital NHS Foundation Trust
    Frimley
  • Gateshead Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust
    Gateshead
  • Inverclyde Royal Hospital, NHS Greater Glasgow and Clyde
    Glasgow
  • Royal Alexandra Hospital, NHS Greater Glasgow and Clyde
    Glasgow
  • Vale of Leven Hospital, NHS Greater Glasgow and Clyde
    Glasgow
  • James Paget Hospital, James Paget University Hospitals NHS Foundation Trust
    Great Yarmouth
  • Royal Surrey County Hospital, Royal Surrey County Hospital NHS Foundation Trust
    Guildford
  • Harrogate and District Hospital, Harrogate and District NHS Foundation Trust
    Harrogate
  • Hull Royal Infirmary, Hull and East Yorkshire NHS Trust
    Hull
  • Ipswich Hospital, East Suffolk and North Essex NHS Foundation Trust
    Ipswich
  • Airedale General Hospital, Airedale NHS Foundation Trust
    Keighley
  • Westmorland General Hospital, University Hospitals of Morecambe Bay NHS Foundation Trust
    Kendal
  • The Queen Elizabeth Hospital, The Queen Elizabeth Hospital Kings Lynn NHS Foundation Trust
    Kings Lynn
  • Royal Lancaster Infirmary, University Hospitals of Morecambe NHS Foundation Trust
    Lancaster
  • Chapel Allerton Hospital, Leeds Teaching Hospitals NHS Foundation Trust
    Leeds
  • Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust
    Leicester
  • Aintree University Hospital, Aintree University Hospitals NHS Trust
    Liverpool
  • Royal Glamorgan Hospital, Cwm Taf University Health Board
    Llantrisant
  • King's College Hospital, King's College Hospital NHS Foundation Trust, London
    London
  • Royal Free Hospital, Royal Free NHS Foundation Trust
    London
  • St George's Hospital, St George's University Hospitals NHS Foundation Trust
    London
  • University College London Hospital, University College London NHS Foundation Trust
    London
  • Manchester Royal Infirmary, Manchester University NHS Foundation Trust
    Manchester
  • Freeman Hospital, The Newcastle-upon-Tyne Hospitals NHS Foundation Trust
    Newcastle
  • North Tyneside General Hospital, Northumbria Healthcare NHS Foundation Trust
    North Shields
  • Northampton General Hospital, Northampton General Hospital NHS Trust
    Northampton
  • Norfolk and Norwich University Hospital, Norfolk and Norwich University Hospitals NHS Foundation Trust
    Norwich
  • Queens Medical Centre, Nottingham University Hospitals NHS Trust
    Nottingham
  • Oxford Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust
    Oxford
  • Peterborough City Hospital, North West Anglia NHS Foundation Trust
    Peterborough
  • Derriford Hospital, University Hospital Plymouth NHS Trust
    Plymouth
  • Poole Hospital, University Hospitals Dorset NHS Foundation Trust
    Poole
  • Minerva Health Centre, Lancashire and South Cumbria NHS Foundation Trust
    Preston
  • Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust
    Preston
  • Salford Royal Hospital, Salford Royal NHS Foundation Trust
    Salford
  • Scarborough General Hospital, York and Scarborough Teaching Hospitals NHS Foundation Trust
    Scarborough
  • Southend University Hospital, Southend University Hospital NHS Foundation Trust
    Southend-on-Sea
  • Lister Hospital, East and North Hertfordshire NHS Trust
    Stevenage
  • Haywood Hospital, Midlands Partnership NHS Foundation Trust
    Stoke-on-Trent
  • Great Western Hospital, The Great Western Hospitals NHS Foundation Trust
    Swindon
  • Torbay Hospital, Torbay and South Devon NHS Foundation Trust
    Torquay
  • Royal Cornwall Hospital, Royal Cornwall Hospitals NHS Trust
    Truro
  • Pinderfields Hospital, Mid Yorkshire Hospitals NHS Trust
    Wakefield
  • Warrington Hospital, Warrington and Halton Hospitals NHS Foundation Trust
    Warrington
  • Royal Hampshire County Hospital, Hampshire Hospitals NHS Foundation Trust
    Winchester
  • Arrowe Park Hospital, Wirral University Hospital NHS Foundation Trust
    Wirral
  • University Hospital Wishaw, NHS Lanarkshire
    Wishaw
  • York Hospital, York and Scarborough Teaching Hospitals NHS Foundation Trust
    York
  • Betsi Cadwaladr University Health Board
    Bangor
    LL57 2PW
  • Queen Elizabeth The Queen Mother Hospital
    Canterbury
    Kent
    CT 1 3NG
  • Whiston Hospital
    Prescot
    Merseyside
    L35 5DR


The study is sponsored by University of Leeds and is in collaboration with University of Oxford.




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Read full details for Trial ID: NCT04102930
Last updated 25 March 2025

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