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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mrs
Sarrah
Peerbux
+44 (0)7866 767516
s.peerbux@imperial.ac.uk
Prof
Alun
Davies
+44 (0)20 3311 7309
a.h.davies@imperial.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
Prevention of venous thromboembolism (VTE) in patients who are deemed to be at low-risk of developing VTE and who undergo day-case/short-stay surgical procedures.
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Hospital acquired thrombosis is a term used to describe blood clots that may form in the legs and lungs after someone is treated in hospital. A clot in the leg can cause swelling, pain and other long-term problems, such as a leg wound (ulcer). If a clot in the leg breaks off and travels to the lungs, it can cause problems with the lungs' ability to transfer oxygen from the air into the blood and may be life threatening. Having surgery increases a person's risk of developing blood clots. There are a number of reasons for this including being unwell, being unable to move during surgery, and moving around less after surgery. To reduce the chance of a blood clot developing, doctors can give blood-thinning medications and elastic stockings that squeeze the leg muscles.
People having short stay surgery are those who are able to go home the same day or those who stay overnight but go home shortly afterwards. These people are at much lower risk of developing a blood clot than those who stay in hospital for longer. These low-risk people are often given elastic stockings to reduce the chance of developing a blood clot. The risks of wearing the stockings are very low but wearing stockings can be uncomfortable. Occasionally some people with poor blood supply to their feet, can develop wounds on one or both of their feet after wearing elastic stockings, but this is rare.
In the UK, there are over a million short stay surgeries performed each year and most of these people are given elastic stockings to wear. Collectively, these elastic stockings cost the NHS a lot of money and it remains unknown if they benefit these people.
A recent study in a different group of people, who are at higher risk of developing a blood clot and are usually given blood-thinning medications, showed that elastic stockings offered no additional benefit compared to just having blood-thinning medications alone. There are currently no up to date studies specifically in this group of people that look at whether these elastic stockings reduce the chance of developing a blood clot.
The purpose of this study is to investigate if it is worthwhile to continue using elastic stockings in people having surgery where the risk of developing blood clots is low.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36653057/ (added 19/01/2023)
You can take part if:
You may not be able to take part if:
Current exclusion criteria as of 12/09/2024:1. Individuals with a contraindication to GCS2. Individuals assessed as being at moderate or high risk of VTE as per the DHRA tool3. Individuals requiring therapeutic anticoagulation4. Individuals requiring pharmacological prophylaxis5. Individuals with thrombophilia/ thrombogenic disorder6. Individuals with a previous history of VTE7. Individuals requiring intermittent pneumatic compression therapy beyond theatre and recovery8. Female patients of childbearing age who have a positive pregnancy test9. Individuals with lower limb immobilisation10. Inability to provide informed consent_____
Previous exclusion criteria as of 14/08/2023 to 12/09/2024:1. Individuals with a contraindication to GCS2. Individuals assessed as being at moderate or high risk of VTE as per the DHRA tool3. Individuals requiring therapeutic anticoagulation4. Individuals with thrombophilia/ thrombogenic disorder5. Individuals with a previous history of VTE6. Individuals requiring intermittent pneumatic compression therapy beyond theatre and recovery7. Individuals requiring extended thromboprophylaxis beyond discharge8. Female patients of childbearing age who have a positive pregnancy test9. Individuals with lower limb immobilisation10. Inability to provide informed consent11. Individuals requiring pharmacological prophylaxis_____
Previous exclusion criteria:1. Individuals with a contraindication to GCS2. Individuals assessed as being at moderate or high-risk of VTE as per the DHRA tool3. Individuals requiring therapeutic anticoagulation4. Individuals with thrombophilia/ thrombogenic disorder5. Individuals with a previous history of VTE6. Individuals requiring intermittent pneumatic compression therapy beyond theatre and recovery7. Individuals requiring extended thromboprophylaxis beyond discharge8. Female patients of childbearing age who have a positive pregnancy test9. Individuals with lower limb immobilisation10. Inability to provide informed consent.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Mrs
Sarrah
Peerbux
+44 (0)7866 767516
s.peerbux@imperial.ac.uk
Prof
Alun
Davies
+44 (0)20 3311 7309
a.h.davies@imperial.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by Imperial College London and funded by National Institute for Health Research.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
