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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Mr
Matthew
Lee
m.j.lee@sheffield.ac.uk
Mr
Matthew
Lee
m.j.lee@sheffield.ac.uk
Cameron
Obie
cameron.obie@nhs.net
Other forms of heart diseaseMalignant neoplasms of digestive organs
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Atrial fibrillation (AF) is an irregular heart beat which can cause symptoms such as shortness of breath and dizziness. It can lead to an increased risk of a blood clot and stroke and is more common in older people. AF occurs in 12-15% of patients following abdominal surgery and is associated with a longer hospital stay and increased risk of stroke within 30 days. Cases of AF post-surgery are likely to increase, as the surgical population is aging.
The diagnosis and treatment of AF is currently focussed on the prevention of complications, which brings with it a burden of drugs and side-effects. Despite therapy, around 10% of patients with AF will suffer a major adverse event such as stroke, heart attack or death within 5 years of diagnosis. Even where major events do not occur, 92% of patients will suffer from significant symptoms from AF. Beyond physical symptoms, anxiety and depression are seen frequently in this patient group and patients have a worse quality of life compared to healthy people. Understanding the risks factors for the development of AF is important. This could enable clinicians to treat a patient before their operation to prevent AF from developing.
This study will determine how many patients have AF and how many develop it after they have undergone colorectal cancer surgery. The patient will be tested for AF before their operation, and at 30 and 90 days after their operation using a 24h heart rhythm monitor. Complications of AF and health services used will be reported. This is a national study involving up to 15 colorectal cancer surgical centres, recruiting 720 patients. The study is funded by the NIHR Research for Patient Benefit (RfPB).
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Type: Active Monitoring;
You can take part if:
You may not be able to take part if:
- Patients aged less than 65 years old - Pre-existing atrial fibrillation (persistent or paroxysmal)
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Mr
Matthew
Lee
m.j.lee@sheffield.ac.uk
Cameron
Obie
cameron.obie@nhs.net
Mr
Matthew
Lee
m.j.lee@sheffield.ac.uk
The study is sponsored by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST and funded by NIHR Central Commissioning Facility (CCF) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 42821
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
