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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Shaman
Jhanji
Ms
Claire
Jacques
+44 (0)2476 522566
VITAL@warwick.ac.uk
Dr
Joyce
Yeung
More information about this study, what is involved and how to take part can be found on the study website.
Total intravenous anaesthesia (TIVA) compared to inhalational volatile-based anaesthesia
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
More than 1.5 million major non-cardiac surgeries are performed in the NHS each year. In the NHS, general anaesthesia is most often given with an inhaled anaesthetic gas. A commonly used alternative is to give anaesthesia using anaesthetic drugs given into the veins, a technique called total intravenous anaesthesia or TIVA. The two techniques may have important differences in how quickly and how well patients recover.
Many anaesthetists believe TIVA is just as safe as inhalational anaesthesia and provides better and faster recovery after surgery. However, others are not convinced that the benefits of using TIVA outweighs the increased cost of this method of anaesthesia. There is a distinct lack of data describing which method might be better. The VITAL trial will measure the benefits of each technique in terms of patient recovery, survival and safety. The results will ensure that the best method of general anaesthesia is being used in the NHS, so that patients can go home quicker, and with reduced cost for the NHS.
VITAL is a multi-centre pragmatic randomised controlled trial, aiming to test whether TIVA (Total Intravenous Anaesthesia) is superior to inhalational anaesthesia.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/38926770/ (added 28/06/2024)
You can take part if:
You may not be able to take part if:
1. Known contraindication to either TIVA or inhalational anaesthesia2. Clinician refusal3. Procedures where the participant is not expected to survive for 30 days4. Previous participation in VITAL trial5. Patient unable to give informed consent or complete questionnaires
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Shaman
Jhanji
Dr
Joyce
Yeung
Ms
Claire
Jacques
+44 (0)2476 522566
VITAL@warwick.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by University of Warwick and funded by NIHR Evaluation, Trials and Studies Co-ordinating Centre (NETSCC); National Institute for Health Research (NIHR) (UK).
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 50027
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
