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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Diabetes mellitus
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Trauma in people with diabetes and damaged nerves can lead to the Charcot foot in which overactive bone breaking cells cause bone damage and destruction. Despite prolonged protection in a cast, the foot becomes deformed. This may lead to lower limb amputation.
Currently, no therapies prevent bone destruction. We propose to develop in the laboratory a bone-strengthening system to be applied at the site of bone damage. We will assess how to reduce the overactivity of bone breaking cells by testing different proteins attached to substances known as bioceramics.
Such material will be used to deliver these proteins to repair injured bones and improve healing.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
• Patients with active Charcot foot complicated by an active foot ulcer and infection
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by King's College London and funded by Medical Research Council (MRC) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 58546
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