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Be Part of Research - Trial Details - A Study to Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

A Study to Investigate the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder

Not Recruiting

Open to: ALL

Age: 1.0 - 35.0

Medical Conditions

Seizures


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This is a multicenter, double-blind, parallel-group, placebo controlled, 2-part study to evaluate the efficacy and safety of ZX008 when used as adjunctive therapy for the treatment of uncontrolled seizures in children and adults with cyclin-dependent kinase like-5 (CDKL5) deficiency disorder (CDD).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2022 Feb 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : ZX008 is supplied as an oral aqueous solution of Fenfluramine Hydrochloride.

Intervention Arm Group : ZX008;ZX008 0.8 mg/kg/day;

Intervention Type : DRUG
Intervention Description : Matching ZX008 placebo is supplied as an oral solution.

Intervention Arm Group : Placebo;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Ep0216 604
    Sheffield
  • Ep0216 607
    Bristol
  • Ep0216 602
    London
  • Ep0216 611
    Manchester


The study is sponsored by Zogenix, Inc.




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Read full details for Trial ID: NCT05064878
Last updated 06 February 2025

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