We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Miss
Tia
Callaghan
+44 (0)114 222 4397
t.callaghan@sheffield.ac.uk
Prof
Rebecca
Gould
+44 (0)20 7679 9225
r.gould@ucl.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
Treatment-resistant generalised anxiety disorder (TR-GAD)
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Generalised anxiety disorder (GAD), characterised by a tendency to worry, is the most common anxiety disorder in older people. Medication and talking therapy are usually offered as forms of treatment, but many do not find them helpful. Guidance on how to help older people manage GAD when it does not respond to such treatments is lacking. In a previous study (the FACTOID study), we developed and tailored a talking therapy intervention to the psychological, physical and cognitive needs of older people with treatment-resistant GAD (TR GAD). This was based on Acceptance and Commitment Therapy (ACT); a form of talking therapy that helps people learn how best to live with distressing thoughts, feelings and sensations, while still doing things that really matter to them. This showed that tailored ACT was acceptable to older people with TR-GAD and it may help improve anxiety, depression and coping. The aim of CONTACT-GAD is to find out whether tailored ACT is helpful for older people with TR-GAD and whether it represents value for money in a larger clinical trial.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
Current participant exclusion criteria as of 05/05/2023:For older people with TR-GAD:1. Judged to lack the capacity to provide fully informed written consent to participate in the trial2. A diagnosis of dementia or intellectual disability using standard diagnostic guidelines, or clinically judged to have moderate or severe cognitive impairment (e.g. due to probable dementia, traumatic brain injury, stroke, etc)3. A diagnosis of an imminently life-limiting illness where they would not be expected to survive for the duration of the study4. Expressing suicidal ideation with active suicidal behaviours/plans and active intent, as assessed using the Columbia-Suicide Severity Rating Scale Screener, for whom an inpatient admission would be more appropriate5. Currently receiving a course of formal psychological therapy delivered by a formally trained psychologist or psychotherapist (e.g. cognitive behavioural therapy, psychodynamic psychotherapy, systemic therapy, counselling, etc), or those who are unwilling to refrain from engaging in such formal psychological therapy should they be randomly allocated to the ACT arm6. Self-report having received ACT in the FACTOID feasibility study7. Having already been randomised in the CONTACT-GAD trial or living with another person who has already been randomised in the CONTACT-GAD trial8. Taking part in clinical trials of other interventions for GAD
Previous participant exclusion criteria:For older people with TR-GAD:1. Judged to lack the capacity to provide fully informed written consent to participate in the trial2. A diagnosis of dementia or intellectual disability using standard diagnostic guidelines, or clinically judged to have moderate or severe cognitive impairment (e.g. due to probable dementia, traumatic brain injury, stroke, etc)3. A diagnosis of an imminently life-limiting illness where they would not be expected to survive for the duration of the study4. Expressing suicidal ideation with active suicidal behaviours/plans and active intent, as assessed using the Geriatric Suicide Ideation Scale, for whom an inpatient admission would be more appropriate5. Currently receiving a course of formal psychological therapy delivered by a formally trained psychologist or psychotherapist (e.g. cognitive behavioural therapy, psychodynamic psychotherapy, systemic therapy, counselling, etc), or those who are unwilling to refrain from engaging in such formal psychological therapy should they be randomly allocated to the ACT arm6. Self-report having received ACT in the FACTOID feasibility study7. Having already been randomised in the CONTACT-GAD trial or living with another person who has already been randomised in the CONTACT-GAD trial8. Taking part in clinical trials of other interventions for GAD
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Miss
Tia
Callaghan
+44 (0)114 222 4397
t.callaghan@sheffield.ac.uk
Prof
Rebecca
Gould
+44 (0)20 7679 9225
r.gould@ucl.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by Camden and Islington NHS Foundation Trust and funded by National Institute for Health and Care Research; National Health Medical Research Centre - National Institute for Health and Care Research (NHMRC-NIHR) Collaborative Research Grant Scheme (Australia).
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 54812
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
