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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Prof
Michael
Gillies
+44 131 242 1642
michael.gillies@nhslothian.scot.nhs.uk
More information about this study, what is involved and how to take part can be found on the study website.
Blood transfusion for recovery from hip surgery
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Hip fracture is the most common serious injury in older people. More than 95% of patients have surgery. This surgery is often high-risk as patients may be frail and have other health problems including heart disease and anaemia (a low blood count). Patients may be in hospital for a long time and need rehabilitation. Up to 35% of surviving patients do not return to their original residence and have a high rate of increased dependency.
Research suggests that 30-40% of these patients have a blood transfusion around the time of operation. However, doctors are uncertain about what level of anaemia transfusions should be given at. Many current guidelines recommend transfusion at a lower level, but there is research which suggests that this level is too low particularly if the patient has a history of heart disease. In these patients, transfusion at a higher level may be better to prevent complications.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
Current exclusion criteria as of 03/07/2025:
1. Objection to RBC transfusion2. Unable to obtain consent (from patient or in accordance with appropriate mental capacity legislation for site)3. Patients for non-operative management or not expected to survive 48 hours4. Patients with a new or suspected acute coronary syndrome meeting 4th Universal Definition during current admission5. Rapid or uncontrolled blood loss resulting in haemodynamic instability6. Chronic anaemia requiring repeated transfusion (eg Myelodysplasia or bone marrow failure syndromes)
_____
Previous participant exclusion criteria as of 17/11/2023:
1. Objection to RBC transfusion2. Unable to obtain consent (from patient or in accordance with appropriate mental capacity legislation for site)3. Patients for non-operative management or not expected to survive 48 hours4. Patients with a new or suspected acute coronary syndrome meeting 4th Universal Definition during current admission5. Rapid or uncontrolled blood loss resulting in haemodynamic instability6. Transfusion dependent/chronic anaemias (eg Myelodysplasia or bone marrow failure syndromes)
_____
Previous participant exclusion criteria:
1. Objection to RBC transfusion2. Unable to obtain consent (from patient or in accordance with appropriate mental capacity legislation for site)3. Patients for non-operative management or not expected to survive 48 hours4. Patients with a new acute coronary syndrome meeting 4th Universal Definition during current admission5. Rapid or uncontrolled blood loss resulting in haemodynamic instability
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Prof
Michael
Gillies
+44 131 242 1642
michael.gillies@nhslothian.scot.nhs.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by University of Edinburgh and NHS Lothian Health Board and funded by NIHR Evaluation, Trials and Studies Co-ordinating Centre (NETSCC); National Institute for Health Research.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 52646
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
