We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Katy
Plant
kmplant@liverpool.ac.uk
Dr
Andreas
Goebel
andreasgoebel@rocketmail.com
Rebecca
Mountford
R.mountford@liverpool.ac.uk
Katy
Plant
kmplant@liverpool.ac.uk
Inflammatory polyarthropathiesSpondylopathiesSystemic connective tissue disorders
This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.
Fibromyalgia syndrome is a widespread chronic pain condition affecting 2-5 % of the world population. The causes of fibromyalgia syndrome are currently unknown. Therefore, treatment options are unsatisfactory, and many patients suffer from unrelenting pain without relief.
Recent research from our group suggests that patients may have immune substances, ‘autoantibodies’, in their blood, which contribute to causing their symptoms. Fibromyalgia is diagnosed in about 20-30% of patients suffering from rheumatological conditions. We wish to assess whether the immune contribution observed in Fibromyalgia patients is responsible for widespread pain in patients diagnosed with rheumatic diseases.
Therefore, we will identify patients with either Rheumatoid Arthritis, Axial Spondyloarthritis or Behçet’s Syndrome. One hundred and fifty patients will be recruited half of which will also have a diagnosis of Fibromyalgia Syndrome. Participants will be asked a series of questions and to complete questionnaires. They will have their skin sensitivity measured using a pressure device and brush to the skin. They will also have images of the front of their eye taken and will donate a blood sample. All of the above will occur during a single visit, in which compensation will be provided for travel. The immune substances from the blood sample will be measured and use in laboratory mouse models to assess their role in widespread pain.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Cross-sectional;
You can take part if:
You may not be able to take part if:
•Pregnant or breast feeding participants •Participants without adequate understanding of the English language •Under the age of 18
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Rebecca
Mountford
R.mountford@liverpool.ac.uk
Katy
Plant
kmplant@liverpool.ac.uk
Katy
Plant
kmplant@liverpool.ac.uk
Dr
Andreas
Goebel
andreasgoebel@rocketmail.com
The study is sponsored by University of Liverpool and funded by Medical Research Council (MRC) .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 54810
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
