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Contact Information:

Matthew Marzetti, MSc +44 1133 923055
m.marzetti@nhs.net


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Be Part of Research - Trial Details - Novel Applications for Sarcoma Assessment
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Novel Applications for Sarcoma Assessment

Recruiting

Open to: ALL

Age: 18.0 - N/A

Leeds

Medical Conditions

Sarcoma

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This research aims to improve the way of deciding whether a lump in soft tissue such as fat or muscle is a type of cancer called a soft tissue sarcoma, or if it is benign (non-cancerous). To do this the investigators will use routine clinical MRI scans, additional quantitative MRI scans and artificial intelligence.

The aims of this research are:

To develop AI algorithms that can accurately classify soft tissue masses as benign or malignant using routine and quantitative MR images.

To classify malignant soft tissue masses into their pathological grade. Compare different AI models on external, unseen testing sets to determine which offers the best performance.

Participants will be asked if they can spend up to a maximum of 10 extra minutes in an MRI scanner so that the extra images can be acquired. A small subset of participants will be invited back so the investigators can check the reproducibility of the images and the AI software.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2023 Mar 2026

OBSERVATIONAL

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : Patients will be asked to remain in the scanner for an additional 10 minutes while we acquire additional quantitative MR images

Intervention Arm Group : Original cohort;Reproducibility cohort;

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : A subset of patients will be invited back for a repeat MRI scan (prior to any treatment for their condition) to help measure reproducibility of our Artificial Intelligence model

Intervention Arm Group : Reproducibility cohort;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Leeds Teaching Hospitals
    Leeds

Matthew Marzetti, MSc +44 1133 923055
m.marzetti@nhs.net



The study is sponsored by The Leeds Teaching Hospitals NHS Trust



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Read full details for Trial ID: NCT06073314
Last updated 08 December 2023

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