Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Susanne Roux ADEPPT@etop.ibcsg.org


Heidi Roschitzki, PhD +41 31 511 94 00
heidi.roschitzki@etop.ibcsg.org


Study Location:

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Be Part of Research - Trial Details - Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status

Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Carcinoma, Non-Small-Cell Lung


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


ADEPPT is an international, multicentre, single-arm phase II trial. The protocol treatment consists of adagrasib, which is administered at a dose of 600 mg orally, twice daily until progression or unacceptable toxicity.The primary objective of this trial is to assess the clinical efficacy of adagrasib treatment, in terms of objective response, in patients with KRASG12C-mutant NSCLC, including the elderly (≥70 years) or patients with poor performance status (ECOG PS=2).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2023 Oct 2025

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : Adagrasib is administered at a dose of 600 mg orally, twice daily until progression or unacceptable toxicity.

Intervention Arm Group : Treatment Arm;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Christie NHS Manchester
    Manchester


The study is sponsored by ETOP IBCSG Partners Foundation and is in collaboration with Mirati Therapeutics Inc..




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Read full details for Trial ID: NCT05673187
Last updated 22 July 2024

This page is to help you find out about a research study and if you may be able to take part

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