Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Study Location:

Skip to Main Content
English | Cymraeg
Be Part of Research - Trial Details - CONNEX-3: A Study to Test Whether Iclepertin Improves Learning and Memory in People With Schizophrenia

CONNEX-3: A Study to Test Whether Iclepertin Improves Learning and Memory in People With Schizophrenia

Completed

Open to: ALL

Age: 18.0 - 50.0

Medical Conditions

Schizophrenia


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study is open to adults with schizophrenia. Schizophrenia can affect the way a person thinks, their memory and their mental functioning. Examples include struggling to remember things, or to read a book or pay attention to a movie. Some people have difficulty calculating the right change or planning a trip so that they arrive on time. The purpose of this study is to find out whether a medicine called iclepertin improves learning and memory in people with schizophrenia.

Participants are put into two groups randomly, which means by chance. One group takes iclepertin tablets and the other group takes placebo tablets. Placebo tablets look like iclepertin tablets but do not contain any medicine. Participants take a tablet once a day for 26 weeks. In addition, all participants take their normal medication for schizophrenia.

During this time, doctors regularly test learning and memory of the participants by use of questionnaires, interviews, and computer tests. The results of the mental ability tests are compared between the groups.

Participants are in the study for about 8 months and visit the study site about 14 times. During this time, doctors regularly check participants' health and take note of any unwanted effects.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Aug 2021 Oct 2024

INTERVENTIONAL

Intervention Type : DRUG
Intervention Description : BI 425809

Intervention Arm Group : Iclepertin treatment group;

Intervention Type : DRUG
Intervention Description : Placebo

Intervention Arm Group : Placebo group;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Western General Hospital
    Edinburgh
    EH4 2XU
  • Queen Elizabeth University Hospital
    Glasgow
    G51 4TF
  • Warneford Hospital
    Oxford
    OX3 7JX
  • Maudsley Hospital
    London
    SE5 8AZ
  • Bodmin Community Hospital
    Bodmin
    PL31 2QT
  • The Fritchie Centre
    Cheltenham
    GL53 9DZ
  • Redesmere
    Chester
    CH2 1BQ
  • Moorgreen Hospital
    Southampton
    SO30 3JB


The study is sponsored by Boehringer Ingelheim




We'd like your feedback

Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.


Is this study information helpful?

What will you do next?

Read full details for Trial ID: NCT04860830
Last updated 07 January 2025

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.