Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Erika Dempsey erika.dempsey@sydney.edu.au


Grace Balicki grace.balicki@sydney.edu.au


Study Location:

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Be Part of Research - Trial Details - Randomised Evaluation of Sodium Dialysate Levels on Vascular Events

Randomised Evaluation of Sodium Dialysate Levels on Vascular Events

Medical Conditions

Kidney Diseases
Kidney Failure, Chronic


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This global study will assess the effect of randomising dialysis sites to one of two default dialysate sodium concentrations in current practice, 140mmol/l and 137mmol/l, on major cardiovascular events and death in patients receiving maintenance haemodialysis.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jun 2016 Dec 2026

Publications

"See EJ, Polkinghorne KR. Volume management in haemodialysis patients. Curr Opin Nephrol Hypertens. 2020 Nov;29(6):663-670. doi: 10.1097/MNH.0000000000000642."; "32889978"

INTERVENTIONAL

Intervention Type : OTHER
Intervention Description : Default defined here as use of allocated dialysate sodium concentration for at least 90% of delivered dialysis sessions.

Intervention Arm Group : 137mmol/l;

Intervention Type : OTHER
Intervention Description : Default defined here as use of allocated dialysate sodium concentration for at least 90% of delivered dialysis sessions.

Intervention Arm Group : 140mmol/l;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Royal London Hospital
    London
  • Broomfield Hospital
    Broomfield
  • Queen's Hospital
    Romford
  • Macclesfield District General Hospital
    Macclesfield
  • Friarage Hospital
    Northallerton
  • Whipps Cross Hospital
    London
  • County Hospital
    Stafford
  • York Hospital
    York
  • Altrincham General Hospital Dialysis Unit
    Altrincham
  • Barnet Satellite Unit
    Barnet
  • Bolton Kidney Care Centre
    Bolton
  • Brighton Sussex Kidney Unit
    Brighton
  • Colchester (Diaverum)
    Colchester
  • Clay Lane
    Coventry
  • Edgware Satellite Unit
    Edgware
  • Heavitree
    Exeter
  • Hayes Hospital
    Hayes
  • Fresenius Hull Dialysis Unit
    Hull
  • King George Hospital
    London
  • Mary Rankin Satellite Unit
    London
  • James Cook
    Middlesbrough
  • North Ormesby
    Middlesbrough
  • Newham Hospital
    Plaistow
  • Renal G Floor
    Sheffield
  • Tottenham Hale Satellite Unit
    Tottenham
  • Wigan Renal Unit
    Wigan
  • Tameside Renal Dialysis Unit
    Ashton-under-Lyne
  • Barnsley Dialysis Unit
    Barnsley
  • Bath Dialysis Unit
    Bath
  • Bedford Renal Unit
    Bedford
  • Bexhill Dialysis Unit
    Bexhill-on-Sea
  • Hexagon Towers Dialysis Unit
    Blackley
  • St Luke's Hospital Renal Ward
    Bradford
  • Bridgwater Dialysis Unit
    Bridgwater
  • Cossham Dialysis Unit
    Bristol
  • South Bristol Dialysis Unit
    Bristol
  • Bromley Dialysis Unit
    Bromley
  • Cannock Haemodialysis Unit
    Cannock
  • Chesterfield Dialysis Unit
    Chesterfield
  • Clacton (Diaverum)
    Clacton-on-Sea
  • University Hospitals Coventry & Warwickshire Main Unit
    Coventry
  • Crawley Dialysis Unit
    Crawley
  • Leighton
    Crewe
  • Cromer Hospital Dialysis Unit
    Cromer
  • Darlington Dialysis Unit
    Darlington
  • Dartford Dialysis Unit
    Dartford
  • Dover Renal Unit
    Dover
  • Epsom Dialysis Unit
    Epsom
  • Farnborough Dialysis Unit
    Farnborough
  • Cotswold Dialysis Centre
    Gloucester
  • Severn
    Gloucester
  • James Paget Renal Unit
    Great Yarmouth
  • Grimsby Renal Unit
    Grimsby
  • Harlow Renal Unit
    Harlow
  • Honiton
    Honiton
  • Chiltern Renal Unit
    Houghton Regis
  • West Middlesex
    Isleworth
  • Kingston Satellite Dialysis Unit
    Kingston
  • Collierswood Dialysis Unit
    London
  • North Wandsworth Dialysis Unit
    London
  • Ludlow Dialysis Unit
    Ludlow
  • Manchester Royal Infirmary Renal Dialysis Unit
    Manchester
  • Octagon Renal Satellite
    Manchester
  • Margate Renal Unit
    Margate
  • Harrogate
    North Yorkshire
  • Lucy Deane (George Eliot)
    Nuneaton
  • Oldham Dialysis Unit
    Oldham
  • Eastbourne (Polegate) Dialysis Unit
    Polegate
  • Rochdale Dialysis Unit
    Rochdale
  • Rotherham Dialysis Unit
    Rotherham
  • St Cross (Ash Unit)
    Rugby
  • Salford Renal Unit
    Salford
  • Scarborough
    Scarborough
  • Scunthorpe Dialysis Centre
    Scunthorpe
  • Peter Moorhead Unit
    Sheffield
  • Sheffield Dialysis Unit
    Sheffield
  • Shrewsbury Renal Unit
    Shrewsbury
  • Smethwick Dialysis Centre
    Smethwick
  • St Albans Dialysis Unit
    St Albans
  • Lister Renal Unit
    Stevenage
  • Stockport NHS Dialysis Unit
    Stockport
  • North Tees
    Stockton-on-Tees
  • Royal Stoke
    Stoke-on-Trent
  • Stratford Dialysis Centre
    Stratford-upon-Avon
  • St. Helier Dialysis Unit
    Sutton
  • Sutton Dialysis Unit
    Sutton
  • Taunton Dialysis Centre
    Taunton
  • Hollinswood House Renal Unit
    Telford
  • Croydon Dialysis Unit
    Thornton Heath
  • South Devon Satellite Kidney Unit
    Torquay
  • Ashford Renal Unit
    Willesborough
  • Pond Lane Dialysis Unit
    Wolverhampton
  • Woolwich Dialysis Unit
    Woolwich
  • Worthing Dialysis Unit
    Worthing
  • Easingwold
    York


The study is sponsored by University of Sydney and is in collaboration with Australasian Kidney Trials Network; Australia & New Zealand Dialysis & Transplant Registry; The George Institute for Global Health, India; The George Institute for Global Health, China; Peking University People's Hospital; Institute for Clinical Evaluative Sciences; St. Michaels Hospital; University Hospital Wuerzburg, Medizinische Klinik EINS; Malaysian Society of Nephrology; Malaysian Renal Registry; Comprehensive Clinical Trials Unit, University College London.





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Read full details for Trial ID: NCT02823821
Last updated 01 April 2025

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