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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Prof
David
van Heel
d.vanheel@qmul.ac.uk
Prof
David
van Heel
d.vanheel@qmul.ac.uk
Cerebrovascular diseasesIschaemic heart diseasesOther forms of heart diseaseDiabetes mellitusMetabolic disorders
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
In East London [and second site Bradford], South Asian people have some of the highest rates of heart disease, diabetes, and poor health in the UK. Living with a long-term illness has a major impact on a person’s quality of life and on their family. Genes & Health is a medical research study set up to help fight against these and other major diseases.
Some early aims of the study are:
• To study normal variation in genes in adult Bangladeshi and Pakistani people. Knowing what is normal is important when searching for genes causing inherited childhood diseases.
• To study genes in people with very high and very low cholesterol levels, to better understand why heart disease and stroke occurs.
• To study variation in genes in healthy adults whose parents are related. These studies will tell us how genes work, and help develop new medicines.
• To study genes of people with diabetes, aiming to identify rarer types of diabetes for which more specific treatments can be used.
We will establish a panel of 100,000 local adult volunteers, who will be asked to donate a small saliva (spit) sample and share their GP and hospital medical records in strict confidence with the study team. Volunteers will be asked to give their consent to be contacted again and some (~1000/year) may be invited to participate in further medical research studies on the basis of data gathered from their samples and information. Genes & Health will support many other medical research studies (each with their own separate ethics approval). One study (approval sought in this application) is looking at how genetic variation influences RNA and proteins in blood cells, by inviting selected volunteers to donate 50ml blood. De-identified
information and samples may be made available to approved scientists in academia and industry worldwide.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Cohort study;
You can take part if:
You may not be able to take part if:
- There will be no exclusion on the basis of gender, or disease status. - Patients with mental and learning disabilities are included provided they are deemed competent to consent. However, patients with significant cognitive impairment will be excluded from the study as they may have reduced capacity to both comprehend the research and to agree to participate in it.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
The study is sponsored by Queen Mary University of London and funded by BARTS CHARITY; Medical Research Council (MRC); Wellcome Trust; .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 18124
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
