Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Mrs Emma Bamford
+44 (0)1332 786985
emma.bamford1@nhs.net


Miss Hannah Berntsson
+44 (0)114 222 8278
h.berntsson@sheffield.ac.uk


Miss Hannah Berntsson
+44 (0)114 222 8278
h.berntsson@sheffield.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - Flexor injury rehabilitation splint trial

Flexor injury rehabilitation splint trial

Medical Conditions

Injuries and accidents


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Flexor tendons attach to the muscles in our forearms and give us the ability to bend our fingers. In the UK, more than 7000 people a year cut their flexor tendons. Without surgery to repair the tendons, the fingers would never bend and our hands would become useless. Following surgery, a 'made-to-measure' splint is needed to prevent the repaired tendon from re-rupturing. However, people who have had this operation have told us that wearing a splint is awkward and often means they can not work. They also told us that sometimes they do not wear their splint at all. There are currently three splints available on the NHS: long, short and mini. We do not know which of the three splints is best. The aim of the FIRST study is to determine which splint gives people the best chance of getting back their normal hand use, what is it like to wear each splint, if people wear these as instructed, and whether one splint is better value for money.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

22 Aug 2022 22 Mar 2024

Publications

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/38493121/ (added 18/03/2024)

Participants will be randomised into 3 groups and given either the long, short or mini splint following their surgery. They will be monitored for a year. We will ask questions about their hand and wrist use and how long they had off work. We will measure how much they can move their hand and how strong their hand is. We will also ask if they have any pain in their hand or wrist, or had any other troubles because of their injury. We will put heat sensors in each splint which will monitor how much they are wearing their splint and each patient will be surveyed to find out what aspects of wearing the splint are important to them. Alongside this, we will interview 20 patients and ask them what it was like to wear the splint, we will ask if they removed their splint and why this was. We will investigate the number of appointments people have had and if they needed any extra operations or treatments to fix their hands. All of this information will be used to understand which splint is best clinically and provides the best value for money.


Patients aged 16 years and over who have undergone a zone I/II flexor tendon repair

You can take part if:



You may not be able to take part if:


1. Patients with associated fractures requiring fixation or additional splintage2. Tendon lacerations involving 3 or more fingers3. Revascularization surgery and/or digital nerve reconstructions requiring a nerve graft4. Presented for treatment more than 3 weeks following the original injury5. Patients unable to consent or comply with the rehabilitation regime, for example, due to cognitive, psychological or physical disabilities6. Co-enrolment in another hand trial


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • North Bristol NHS Trust
    Southmead Hospital Southmead Road Westbury-on-trym
    Bristol
    BS10 5NB
  • Queen Alexandras Hospital
    Southwick Hill Road Cosham
    Portsmouth
    PO6 3LY
  • University Hospitals Birmingham NHS Foundation Trust
    Queen Elizabeth Hospital Mindelsohn Way Edgbaston
    Birmingham
    B15 2GW
  • University Hospitals of Leicester NHS Trust
    Leicester Royal Infirmary Infirmary Square
    Leicester
    LE1 5WW
  • Northampton General Hospital NHS Trust
    Cliftonville
    Northampton
    NN1 5BD
  • The Shrewsbury and Telford Hospital NHS Trust
    Mytton Oak Road
    Shrewsbury
    SY3 8XQ
  • Royal United Hospitals Bath NHS Foundation Trust
    Combe Park
    Bath
    BA1 3NG
  • Norfolk and Norwich University Hospitals NHS Foundation Trust
    Colney Lane Colney
    Norwich
    NR4 7UY
  • John Radcliffe Hospital
    Headley Way Headington
    Oxford
    OX3 9DU
  • Royal Free London NHS Foundation Trust
    Royal Free Hospital Pond Street
    London
    NW3 2QG
  • Walsgrave General Hospital
    Clifford Bridge Road
    Coventry
    CV2 2DX
  • James Cook University Hospital
    Marton Road
    Middlesbrough
    TS4 3BW
  • Hull Royal Infirmary
    Anlaby Road
    Hull
    HU3 2JZ
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Freeman Hospital Freeman Road High Heaton
    Newcastle upon Tyne
    NE7 7DN
  • Barts Health NHS Trust
    The Royal London Hospital 80 Newark Street
    London
    E1 2ES
  • NHS Lanarkshire
    14 Beckford Street
    Hamilton
    ML3 0TA
  • Royal Derby Hospital (nuh)
    Uttoxeter Road
    Derby
    DE22 3NE
  • Royal Cornwall Hospital (treliske)
    Treliske
    Truro
    TR1 3LJ
  • Cambridge University Hospitals NHS Foundation Trust
    Addenbrookes Hospital
    Cambridge
    CB2 0AU
  • Chelsea & Westminster Hospital
    369 Fulham Road
    London
    SW10 9NH
  • Swansea Bay University Local Health Board
    One Talbot Gateway, Seaway Drive Seaway Parade Industrial Estate Baglan
    Port Talbot
    SA12 7BR
  • Amersham Hospital
    Whielden Street
    Amersham
    HP7 0JD
  • Salisbury NHS Foundation Trust
    Salisbury District Hospital Odstock Road
    Salisbury
    SP2 8BJ
  • Preston Acute Hospitals NHS Trust
    Royal Preston Hospital Sharoe Green Lane North Fulwood
    Preston
    PR2 9HT
  • St Thomas' Hospital (alliance Medical Scanning)
    St. Thomas's Hospital Westminster Bridge Road
    London
    SE1 7EH
  • Queen Victoria Hospital NHS Foundation Trust
    Holtye Road
    East Grinstead
    RH19 3DZ

The study is providing information in this area as participants will be contributing to important research that will inform treatment choices for patients in future. They will be under close follow-up contact which is normal for those taking part in a research study. All flexor tendon repair patients will have a splint to wear during rehabilitation, whether or not they participate in the study. Splints have the potential risk to be uncomfortable and can cause skin irritation and stiffness. Participants will be provided with site-specific contact details in case they experience any problems with their splint.

Mrs Emma Bamford
+44 (0)1332 786985
emma.bamford1@nhs.net


Miss Hannah Berntsson
+44 (0)114 222 8278
h.berntsson@sheffield.ac.uk


Miss Hannah Berntsson
+44 (0)114 222 8278
h.berntsson@sheffield.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University Hospitals of Derby and Burton NHS Foundation Trust and funded by National Institute for Health and Care Research; Grant Codes: NIHR133582.




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Read full details for Trial ID: ISRCTN10236011

Or CPMS 52908

Last updated 03 May 2024

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