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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Miss Heather Barnes
+44 1865223113
draft3-casp@ndorms.ox.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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Be Part of Research - Trial Details - Distal Radius Acute Fracture Trial 3 - a randomised study to compare a plaster cast to a removable splint for patients with a broken wrist

Distal Radius Acute Fracture Trial 3 - a randomised study to compare a plaster cast to a removable splint for patients with a broken wrist

Medical Conditions

Fractures in the distal radius that do not need manipulation


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


There are over 100,000 fractures of the wrist (distal radius) in the UK each year; 6% of all women will have sustained such a fracture by the age of 80 and 9% by the age of 90. Following a fracture of the distal radius, if the bone fragments have remained in their normal alignment, the fracture can be treated with a support for the injured wrist, which will provide pain relief and protects from further damage as the fracture heals. Over three quarters of all distal radius fractures in adults fall into this category and outcomes are generally good.

For those patients whose fracture remains aligned, usual care is to provide the patient with a temporary ‘backslab’ plaster cast in the emergency department. The patient is then referred to the orthopaedic fracture clinic where the backslab is converted to a full fibre-glass cast. The patient has to return to the fracture clinic 4-6 weeks later to have their cast removed.

Recently, there has been some evidence that a removable wrist splint may provide the patient with the same support as a cast while their fracture heals. A splint can be removed by the patient themselves thereby avoiding additional visits to the hospital. This could be more convenient for patients and save money for the NHS.

This study will compare wrist function and pain in patients with a fracture of the distal radius
treated with usual care in a cast with standard follow-up versus a removable wrist splint with
discharge from the emergency department.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

20 Feb 2023 01 Nov 2024

1894 adult patients with a fracture of their distal radius will be invited to take part from hospitals across the UK. Half of those that agree to take part will be treated in a cast and half in a removable splint. All of the patients will be given the same information and advice about their injury and their recovery. Which treatment a person gets will be decided by a computer to ensure a fair comparison. Everyone has an equal chance of getting either treatment. During the first two weeks, we will monitor the patients’ pain and after three, six and twelve months everyone will receive a questionnaire. The questionnaires will ask about what activities they are able to do, their quality of life, any problems they might have and any costs that have been incurred because of the injury.


There are over 100,000 fractures of the wrist (distal radius) in the UK each year; 6% of all women will have sustained such a fracture by the age of 80 and 9% by the age of 90. Following a fracture of the distal radius, if the bone fragments have remained in their normal alignment, the fracture can be treated with a support for the injured wrist, which will provide pain relief and protects from further damage as the fracture heals. Over three quarters of all distal radius fractures in adults fall into this category and outcomes are generally good.

For those patients whose fracture remains aligned, usual care is to provide the patient with a temporary ‘backslab’ plaster cast in the emergency department. The patient is then referred to the orthopaedic fracture clinic where the backslab is converted to a full fibre-glass cast. The patient has to return to the fracture clinic 4-6 weeks later to have their cast removed.

Recently, there has been some evidence that a removable wrist splint may provide the patient with the same support as a cast while their fracture heals. A splint can be removed by the patient themselves thereby avoiding additional visits to the hospital. This could be more convenient for patients and save money for the NHS.

This study will compare wrist function and pain in patients with a fracture of the distal radius
treated with usual care in a cast with standard follow-up versus a removable wrist splint with
discharge from the emergency department.

Who can participate?
Patients aged 16 years and older with an acute fracture of the distal radius who, in the opinion of the treating clinician, do not require a manipulation of the fracture. Patients presenting to the research team more than two weeks after they sustain their injury; those who have an open fracture; or patients who would be unable to follow trial procedures will be excluded.

What does the study involve?
1894 adult patients with a fracture of their distal radius will be invited to take part from hospitals across the UK. Half of those that agree to take part will be treated in a cast and half in a removable splint. All of the patients will be given the same information and advice about their injury and their recovery. Which treatment a person gets will be decided by a computer to ensure a fair comparison. Everyone has an equal chance of getting either treatment. During the first two weeks, we will monitor the patients’ pain and after three, six and twelve months everyone will receive a questionnaire. The questionnaires will ask about what activities they are able to do, their quality of life, any problems they might have and any costs that have been incurred because of the injury.

What are the possible benefits and risks of participating?
Both treatments in this study are used across the NHS at the moment. They are not new or experimental. We do not know whether there is a difference in recovery for patients who
get a cast or a splint. This is why we are doing the research. If patients join in, they will help us make treatment for future patients with similar injuries better. This study will also give us information about the best use of resources within the NHS. There are some standard risks of having a plaster cast or splint, such as rubbing on the skin, feelings of pins and needles, or numbness (temporary loss of feeling) and stiffness. These risks are the same for any patient having these treatments. They are not affected by whether patients join this research study or not.

You can take part if:



You may not be able to take part if:


1. Present to research team more than 2 weeks post-injury2. The fracture is open (Gustilo and Anderson > 1)3. They are unable to adhere to trial procedures, e.g. patients with permanent cognitive impairment, or other concomitant severe injuries e.g. head injury.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Musgrove Park Hospital (taunton)
    Musgrove Park Hospital
    Taunton
    TA1 5DA
  • John Radcliffe Hospital
    Headley Way
    Oxford
    OX3 9DU
  • Derriford Hospital
    Derriford Road
    Plymouth
    PL6 8DH
  • James Cook University Hospital
    Marton Road
    Middlesbrough
    TS4 3BW
  • Yeovil District Hospital
    Higher Kingston
    Yeovil
    BA21 4AT
  • Addenbrookes
    Addenbrookes Hospital Hills Road
    Cambridge
    CB2 0QQ
  • Royal Berkshire Hospital
    Royal Berkshire Hospital London Road
    Reading
    RG1 5AN
  • Glan Clwd Hospital
    Ysbyty Glan Clwydd Bodelwyddan
    Rhyl
    LL18 5UJ
  • Kettering General Hospital
    Rothwell Road
    Kettering
    NN16 8UZ
  • Kings Mill Hospital
    Mansfield Road
    Sutton-in-Ashfield
    NG17 4JL
  • Norfolk & Norwich University Hospital
    Colney Lane Colney
    Norwich
    NR4 7UY
  • Aintree University Hospital
    Lower Lane
    Liverpool
    L9 7AL
  • Princess Alexandra Hospital
    Hamstel Road
    Harlow
    CM20 1QX
  • Salford Royal Hospital
    Stott Lane Eccles
    Salford
    M6 8HD
  • Royal Derby Hospital (nuh)
    Uttoxeter Road
    Derby
    DE22 3NE
  • Royal Devon and Exeter Hospital
    Royal Devon & Exeter Hospital Barrack Road
    Exeter
    EX2 5DW
  • University Hospital of North Tees
    Hardwick Road
    Stockton-on-tees
    TS19 8PE
  • Wrexham Maelor Hospital
    Croesnewydd Road Wrexham Technology Park
    Wrexham
    LL13 7TD
  • Airedale General
    Airedale General Hospital Skipton Road, Steeton
    Keighley
    BD20 6TD
  • Royal Hampshire County Hospital
    Romsey Road
    Winchester
    SO22 5DG
  • Frimley Park Hospital
    Frimley Park Scanning Centre Portsmouth Road Frimley
    Camberley
    GU16 7UJ
  • The Royal Glamorgan Hospital
    Ynysmaerdy
    Pontyclun
    CF72 8XR
  • Sandwell General Hospital
    Lyndon
    West Bromwich
    B71 4HJ
  • Wexham Park Hospital
    Wexham Street Wexham
    Slough
    SL2 4HL
  • North West London Hospitals NHS Trust
    Northwick Park Hospital Watford Road
    Harrow
    HA1 3UJ
  • St. Georges Hospital
    Blackshaw Road
    London
    SW17 0QT
  • Royal Liverpool University Hospital
    Mount Vernon St
    Liverpool
    L7 8YE
  • South Tyneside District Hospital
    South Tyneside District Hospit Harton Lane
    South Shields
    NE34 0PL
  • Southmead Hospital
    Southmead Way
    Bristol
    BS10 5NB
  • Queens Hospital
    Queens Road
    Croydon
    CR9 2PQ

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.

Miss Heather Barnes
+44 1865223113
draft3-casp@ndorms.ox.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University of Oxford and funded by NIHR Evaluation, Trials and Studies Co-ordinating Centre (NETSCC).




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Read full details for Trial ID: ISRCTN66692543

Or CPMS 54355

Last updated 14 February 2024

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