Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Ms Sara Buttery
+44 (0)207 351 8029
s.buttery@rbht.nhs.uk


Study Location:

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Be Part of Research - Trial Details - UK lung volume reduction trial

UK lung volume reduction trial

Medical Conditions

Emphysema


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Chronic obstructive pulmonary disease (COPD) is the name for a group of lung conditions that cause breathing difficulties. In some patients with emphysema (damage to the air sacs in the lungs), an operation called lung volume reduction surgery is effective at removing the worst affected area of the lung. New techniques have been developed where emphysema can be treated using a fibre-optic camera called a bronchoscope. Studies have shown that using a bronchoscope to place implantable medical devices called endobronchial valves into the airways can be very effective in carefully selected patients and the technique is now being adopted in hospitals across the UK. The aim of this study is to collect data from people undergoing these procedures at hospitals across the UK to find out how well they work in practice and what factors influence response.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Dec 2016 31 Mar 2026

The study involves collecting routine data about lung volume reduction procedures onto a central database. Results from across the UK can then be used to improve understanding of the procedures. Participants are not required to do anything in addition. Data is collected at the start of the study and at 3-month and 12-month follow up, including lung function data, measures of exercise capacity (maximum amount of exercise that a patient can sustain), questionnaires about health status and CT scan results.


Patients aged over 18 with emphysema undergoing a lung volume reduction procedure

You can take part if:



You may not be able to take part if:


Not meeting the inclusion criteria


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • University Hospitals Bristol NHS Foundation Trust
    Marlborough Street
    Bristol
    BS1 3NU
  • University Hospital of Wales
    Heath Park
    Cardiff
    CF14 4XW
  • Addenbrooke's Hospital
    Hills Rd
    Cambridge
    CB2 0QQ
  • Heart of England NHS Foundation Trust
    Bordesley Green East
    Birmingham
    B9 5ST
  • Leeds Teaching Hospitals NHS Trust
    Beckett Street
    Leeds
    LS9 7TF
  • Royal Brompton Hospital
    Fulham Rd
    London
    SW3 6NP
  • Glenfield Hospital
    Groby Rd
    Leicester
    LE5 4QF
  • Oxford Health NHS Foundation Trust
    John Smith Dr
    Oxford
    OX4 2GX
  • Liverpool Heart and Chest NHS Foundation Trust
    Thomas Dr
    Liverpool
    L14 3PE
  • University Hospital of South Manchester NHS Foundation Trust
    Southmoor Rd
    Manchester
    M23 9LT
  • Sheffield Teaching Hospitals NHS Foundation Trust
    Herries Rd
    S5 7AU
  • The Newcastle on Tyne Hospitals NHS Foundation Trust
    Freeman Road
    Newcastle on Tyne
    NE7 7DN
  • The Royal Wolverhampton Hospitals NHS Trust
    Wolverhampton Rd
    Wolverhampton
    WV10 0QP

This study will make it easier to assess lung volume reduction procedures and bring new treatments into play more quickly. There are no risks to participants.


The study is sponsored by Imperial College London and funded by British Lung Foundation.




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Read full details for Trial ID: ISRCTN16371361
Last updated 12 October 2022

This page is to help you find out about a research study and if you may be able to take part

You can print or share the study information with your GP/healthcare provider or contact the research team directly.