Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr Steve Peacey
+44 (0)1274 382019
srpeacey@talk21.com


Study Location:

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Be Part of Research - Trial Details - Glucocorticoid replacement therapy and fibrinolysis.
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Glucocorticoid replacement therapy and fibrinolysis.

Not Recruiting

Open to: All Genders

Age: Adult

Bradford

Medical Conditions

Nutritional, Metabolic, Endocrine: Hypopituitarism

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Not provided at time of registration

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

19 Nov 2004 01 Apr 2007

Publications

2010 Abstract results in http://www.endocrine-abstracts.org/ea/0021/ea0021p261.htm results presented at Society for Endocrinology BES

Interventional

Intervention Type : Other
Intervention Description : The study will be of randomised, open-label, crossover design, comparing the effects of traditional glucocorticoid replacement regimens versus modern regimens on fibrinolytic parameters in patients with hypopituitarism.Patients will have a two week period of treatment with either their current 'optimised' treatment regimen or with a higher dose (approx 30 - 50%) traditional type regimen. At the end of each two week period they will be admitted to a day case ward for hourly blood sampling over a 10 hour period. Blood will be taken for cortisol levels (adrenal steroid) in a standard fashion ( a cortisol day profile) and for fibrinolytic parameters (i.e twice in total).




You can take part if:



You may not be able to take part if:


1. Subjects requiring systematic steroid therapy2. Subjects taking HRT or oral contraceptive3. Subjects who are currently pregnant or who had recent pregnancy or abortion4. Subjects with known malignancy5. Subjects with known coagulopathy6. Subjects who are currently taking or have recently taken anticoagulant therapy


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Diabetes & Endocrinology
    Bradford
    BD9 6RJ

This information has not yet been provided by the study team. You'll have an opportunity to discuss any risks and benefits that may be associated with this study prior to consenting to taking part.

Dr Steve Peacey
+44 (0)1274 382019
srpeacey@talk21.com



The study is sponsored by Department of Health and funded by Bradford Teaching Hospitals NHS Foundation Trust (UK) Own account but no NHS R&D Support Funding.



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Read full details for Trial ID: ISRCTN93511659
Last updated 31 August 2010

This page is to help you find out about a research study and if you may be able to take part

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