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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
GASTRIC-PICU
Team
-
gastric@icnarc.org
Prof
Lyvonne
Tume
+44 (0)7710412142
Lyvonne.tume@edgehill.ac.uk
Ms
Irene
Chang
+44 (0)204 513 6249
irene.chang@icnarc.org
More information about this study, what is involved and how to take part can be found on the study website.
Oral and Gastrointestinal
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Most children in intensive care cannot eat normally by mouth and require feeding into their stomach via a tube (a nasogastric (NG) tube or gastrostomy). It is important to provide enough calories to children through their feeds while they are critically ill, as this can help them to get off the ventilator faster, improves how quickly wounds heal and generally helps them to recover better from their illness. Ensuring children in intensive care have enough calories from feeds is a big challenge. We know from large worldwide studies that most children in intensive care get only around half of the calories they need. This is mainly due to their feeds being stopped. The most common reason is that the amount of fluid in the stomach is felt to be ‘large’. Across the UK, it is a common practice in all Paediatric Intensive Care Units (PICU) for nurses to check how much food is in the stomach. A syringe is attached to the end of the feeding tube and the child’s stomach contents are gently ‘sucked out’. This is to see how much fluid is in the child’s stomach and see how well the child is digesting their feed. This is called the gastric residual volume or GRV, often referred to as an ‘aspirate’. If a child has a ‘large’ GRV, often feeding is stopped. However, the amount of fluid in the child’s stomach is affected by many things, not just how much we feed them, but also how much gastric juice their stomach produces and some of the medicines we use slow down the stomach’s actions. The measurement of this (GRV) through the NG tube or gastrostomy is known to be quite inaccurate. Therefore, a decision may be taken to stop feeds, or not to increase feeds, when there is no need to. We do not know whether it is better to measure GRV routinely or not and this is why we are doing this study. This study aims to determine the clinical and cost-effectiveness of no routine GRV measurement to guide enteral feeding and to determine if it is non-inferior to standard at least 6 hourly GRV measurements in mechanically ventilated children admitted to PICU.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
You can take part if:
You may not be able to take part if:
1. Post-pyloric feeding or jejunostomy 2. End-of-life care plan in place with limitation of resuscitation 3. Children on long-term mechanical ventilation 4. Current or recent gut pathology or surgery (e.g., necrotising enterocolitis (NEC), active GI bleeding, or any intestinal surgery)5. Known to have been enrolled in the GASTRIC-PICU trial in the last 6 months
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Ms
Irene
Chang
+44 (0)204 513 6249
irene.chang@icnarc.org
Dr
GASTRIC-PICU
Team
-
gastric@icnarc.org
Prof
Lyvonne
Tume
+44 (0)7710412142
Lyvonne.tume@edgehill.ac.uk
More information about this study, what is involved and how to take part can be found on the study website.
The study is sponsored by Intensive Care National Audit & Research Centre and funded by National Institute for Health and Care Research.
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Or CPMS 54988
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
