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Be Part of Research - Trial Details - Whole-Body Photobiomodulation and Chronic Pain Trial

Whole-Body Photobiomodulation and Chronic Pain Trial

Recruiting

Open to: ALL

Age: 18.0 - 100.0

Medical Conditions

Chronic Pain


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


Chronic pain is a common long-term condition that can affect any area throughout the body. Individuals suffering with chronic pain often have associated fatigue, sleep and mood disturbances.

Current treatments for chronic pain include a variety of both medicine-based approaches and non-medical approaches such as exercise and psychology treatments. Patients often take a combination of medications such as antidepressants and strong medications like morphine - which are not always effective, and often associated with several troublesome side effects. Despite physical activity being a common and helpful treatment, evidence shows that patients with chronic pain can find it difficult to engage for a variety of reasons. It would be helpful to see if other non-medication based approaches will be an acceptable treatment to those suffering with chronic pain.

Photobiomodulation (PBM) therapy describes a safe, non-invasive low-energy light therapy that has been successful in treating a variety of chronic pain conditions. Cells absorb light to produce a series of reactions that culminate in pain relief, reduced inflammation, and tissue repair. Most studies examining effects of PBM have consisted of a small hand-held probe focused on specific painful areas. There are a cohort of chronic pain conditions that encompass widespread throughout the back, neck and joints, such as fibromyalgia (FM). Whole-body PBM therapy is able to treat a large area of the body in a short space of time.

The main purpose of the study is to determine feasibility, with a view to guiding a definitive Randomised Controlled Trial (RCT), in terms of: feasibility of eligibility criteria, recruitment rates, acceptability of trial device in the chronic pain population, and acceptability of outcome measures.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Jan 2022 Sep 2022

Publications

"Fitzmaurice B, Heneghan NR, Rayen A, Soundy A. Whole-body photobiomodulation therapy for chronic pain: a protocol for a feasibility trial. BMJ Open. 2022 Jun 29;12(6):e060058. doi: 10.1136/bmjopen-2021-060058."; "35768101"

INTERVENTIONAL

Intervention Type : DEVICE
Intervention Description : * All participants entering the trial will receive a course of whole-body PBM therapy* The NovoTHOR Whole-Body PBM therapy device consists of a hinged, clamshell design with light-emitting diodes (LEDs) arranged to emit near-infrared and visible red light therapy is delivered to the entire body at once.* Participants will be expected to lie horizontal in the device with the lid as closed as they are comfortable with.* 18 sessions is the currently recommended and widely instituted and accepted practice with the NovoTHOR device.* The LED equipment delivers red and near infrared light therapy to the participant* Session 1 = 6 minutes* Session 2 = 12 minutes* Sessions 3-18 = 20 minutes* Timescale: 3 treatments/week for 6 weeks* The dosage of LED light (also known as 'fluence') will be equivalent to 25J/cm2. The device will supply a dual wavelength of red and near-infrared light with a 50:50 ratio; 660nm and 850nm respectively

Intervention Arm Group : Intervention Group;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Sandwell and West Birmingham NHS TRUST
    Birmingham


The study is sponsored by Sandwell & West Birmingham Hospitals NHS Trust




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Read full details for Trial ID: NCT05069363
Last updated 26 June 2022

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