Toxicity from biologic therapy (BSRBR)

This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.

The BSRBR-RA study tracks the progress of people with rheumatoid arthritis (RA) who have been prescribed biologic (including biosimilar) and other targeted therapies in the UK, to monitor the long-term safety of these drugs.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Observational

Observational type: Cohort study;

Biologic naive if entering the anti-TNF comparison cohort (Humira, Enbrel, Remicade).

Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

• Airedale General Hospital
  Skipton Road
  steeton
  Keighley
  West Yorkshire
  BD20 6TD
  
• Queen's Hospital
  Rom Valley Way
  Romford
  Essex
  RM7 0AG
  
• King George Hospital
  Barley Lane
  Ilford
  Essex
  IG3 8YB
  
• Whipps Cross University Hospital
  Whipps Cross Road
  London
  Greater London
  E11 1NR
  
• Cardiff & Vale University Lhb
  Woodland House
  maes-y-coed Road
  Cardiff
  CF14 4HH
  
• Ipswich Hospital
  Heath Road
  Ipswich
  Suffolk
  IP4 5PD
  
• Croydon University Hospital
  London Road
  Croydon
  Surrey
  CR7 7YE
  
• Royal Blackburn Hospital
  Haslingden Road
  Blackburn
  Lancashire
  BB2 3HH
  
• Guy's Hospital
  Great Maze Pond
  London
  Greater London
  SE1 9RT
  
• Harrogate District Hospital
  Lancaster Park Road
  Harrogate
  North Yorkshire
  HG2 7SX
  
• Homerton University Hospital
  Homerton Row
  London
  Greater London
  E9 6SR
  
• King's College Hospital (denmark Hill)
  Denmark Hill
  London
  Greater London
  SE5 9RS
  
• Northwick Park Hospital
  Watford Road
  Harrow
  Middlesex
  HA1 3UJ
  
• Luton & Dunstable Hospital
  Lewsey Road
  Luton
  Bedfordshire
  LU4 0DZ
  
• Pontefract General Infirmary
  Friarwood Lane
  Pontefract
  West Yorkshire
  WF8 1PL
  
• Pinderfields General Hospital
  Aberford Road
  Wakefield
  West Yorkshire
  WF1 4DG
  
• Dewsbury & District Hospital
  Halifax Road
  Dewsbury
  West Yorkshire
  WF13 4HS
  
• Milton Keynes Hospital
  Standing Way
  eaglestone
  Milton Keynes
  Buckinghamshire
  MK6 5LD
  
• Ninewells Hospital
  Ninewells Avenue
  Dundee
  Angus
  DD1 9SY
  
• Norfolk & Norwich University Hospital
  Colney Lane
  colney
  Norwich
  Norfolk
  NR4 7UY
  
• North Middlesex Hospital
  Sterling Way
  London
  Greater London
  N18 1QX
  
• Diana, Princess Of Wales Hospital
  Scartho Road
  Grimsby
  South Humberside
  DN33 2BA
  
• ROCHDALE INFIRMARY
  RW604@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Derriford Hospital
  Derriford Road
  crownhill
  Plymouth
  Devon
  PL6 8DH
  
• Royal Berkshire Hospital
  London Road
  Reading
  Berkshire
  RG1 5AN
  
• Royal Cornwall Hospital (treliske)
  Treliske
  Truro
  Cornwall
  TR1 3LJ
  
• North Devon District Hospital
  Raleigh Park
  Barnstaple
  Devon
  EX31 4JB
  
• Royal Free Hospital
  Pond Street
  London
  Greater London
  NW3 2QG
  
• Salford Royal
  Stott Lane
  Salford
  Greater Manchester
  M6 8HD
  
• Musgrove Park Hospital
  Musgrove Park
  Taunton
  TA1 5DA
  
• Greenfields Day Centre
  West Bow House
  milton Place
  Bridgwater
  Somerset
  TA6 3RT
  
• Yeovil District Hospital
  Yeovil District Hospital
  higher Kingston
  Yeovil
  BA21 4AT
  
• Southend Hospital
  Prittlewell Chase
  Westcliff-on-sea
  Essex
  SS0 0RY
  
• Southport & Formby District General Hospital
  Town Lane
  Southport
  Merseyside
  PR8 6PN
  
• St George's Hospital (tooting)
  Blackshaw Road
  London
  Greater London
  SW17 0QT
  
• Russells Hall Hospital
  Pensnett Road
  Dudley
  West Midlands
  DY1 2HQ
  
• Freeman Hospital
  Freeman Road
  high Heaton
  Newcastle Upon Tyne
  Tyne And Wear
  NE7 7DN
  
• Princess Alexandra Hospital
  Hamstel Road
  Harlow
  Essex
  CM20 1QX
  
• Rotherham District General Hospital
  Moorgate Road
  Rotherham
  South Yorkshire
  S60 2UD
  
• New Cross Hospital
  Wolverhampton Road
  heath Town
  Wolverhampton
  West Midlands
  WV10 0QP
  
• The Whittington Hospital
  Magdala Avenue
  London
  Greater London
  N19 5NF
  
• University College Hospital
  235 Euston Road
  London
  Greater London
  NW1 2BU
  
• Weston General Hospital
  Grange Road, Uphill
  Weston-super-mare
  Avon
  BS23 4TQ
  
• University Hospital (coventry)
  Clifford Bridge Road
  Coventry
  West Midlands
  CV2 2DX
  
• Royal Lancaster Infirmary
  Ashton Road
  Lancaster
  Lancashire
  LA1 4RP
  
• West Suffolk Hospital
  Hardwick Lane
  Bury St. Edmunds
  Suffolk
  IP33 2QZ
  
• Arrowe Park Hospital
  Arrowe Park Road
  upton
  Wirral
  Merseyside
  CH49 5PE
  
• Worcestershire Royal Hospital
  Charles Hastings Way
  Worcester
  Worcestershire
  WR5 1DD
  
• Hereford County Hospital
  Union Walk
  Hereford
  Herefordshire
  HR1 2ER
  
• Yeovil District Hospital
  Higher Kingston
  Yeovil
  Somerset
  BA21 4AT
  
• Barnsley Hospital
  Gawber Road
  Barnsley
  South Yorkshire
  S75 2EP
  
• FAIRFIELD GENERAL HOSPITAL
  RW601@2.16.840.1.113883.2.1.3.2.4.18.48
  
• ROYAL OLDHAM HOSPITAL
  RW603@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Barnet Hospital
  Wellhouse Lane
  Barnet
  Hertfordshire
  EN5 3DJ
  
• Stepping Hill Hospital
  Poplar Grove
  Stockport
  Cheshire
  SK2 7JE
  
• Queen Elizabeth Hospital
  Queen Elizabeth Medical Centre
  edgbaston
  Birmingham
  West Midlands
  B15 2TH
  
• Leicester Royal Infirmary
  Infirmary Square
  Leicester
  Leicestershire
  LE1 5WW
  
• University Hospital Aintree
  Lower Lane
  Liverpool
  Merseyside
  L9 7AL
  
• MUSGROVE PARK HOSPITAL
  RBA11@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Southampton General Hospital
  Tremona Road
  Southampton
  Hampshire
  SO16 6YD
  
• Colchester General Hospital
  Turner Road
  Colchester
  Essex
  CO4 5JL
  
• St Helier Hospital
  Wrythe Lane
  Carshalton
  Surrey
  SM5 1AA
  
• The Great Western Hospital
  Marlborough Road
  Swindon
  Wiltshire
  SN3 6BB
  
• Sandwell General Hospital
  Lyndon
  West Bromwich
  West Midlands
  B71 4HJ
  
• Nevill Hall Hospital
  Brecon Road
  Abergavenny
  Gwent
  NP7 7EG
  
• Stoke Mandeville Hospital
  Mandeville Road
  Aylesbury
  Buckinghamshire
  HP21 8AL
  
• Countess Of Chester Hospital
  The Countess Of Chester Health Park
  Chester
  Cheshire
  CH2 1UL
  
• Burton Hospital
  Queens Hospital
  belvedere Road
  Burton-on-trent
  Staffordshire
  DE13 0RB
  
• Royal Derby Hospital
  Uttoxeter Road
  Derby
  Derbyshire
  DE22 3NE
  
• Lister Hospital
  Coreys Mill Lane
  Stevenage
  Hertfordshire
  SG1 4AB
  
• Royal Hampshire County Hospital
  Romsey Road
  Winchester
  Hampshire
  SO22 5DG
  
• Lantern Centre
  Vicarage Lane
  fulwood
  Preston
  Lancashire
  PR2 8DW
  
• Northampton General Hospital (acute)
  Cliftonville
  Northampton
  Northamptonshire
  NN1 5BD
  
• POOLE GENERAL HOSPITAL
  RD300@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Basildon Hospital
  Nethermayne
  Basildon
  Essex
  SS16 5NL
  
• Solihull Hospital
  Lode Lane
  Solihull
  West Midlands
  B91 2JL
  
• Poole Hospital
  Longfleet Road
  Poole
  BH15 2JB
  
• Christchurch Hospital
  Fairmile Road
  Christchurch
  BH23 2JX
  
• Queen Alexandra Hospital
  Southwick Hill Road
  cosham
  Portsmouth
  Hampshire
  PO6 3LY
  
• Royal United Hospital
  Combe Park
  Bath
  Avon
  BA1 3NG
  
• Royal Hallamshire Hospital
  Glossop Road
  Sheffield
  South Yorkshire
  S10 2JF
  
• Aneurin Bevan University Lhb
  Headquarters - St Cadoc's Hospital
  lodge Road
  caerleon
  Newport
  Gwent
  NP18 3XQ
  
• Lancashire & South Cumbria NHS Foundation Trust
  Sceptre Point
  sceptre Way
  bamber Bridge
  Preston
  PR5 6AW
  
• Royal Liverpool University Hospital
  Prescot Street
  Liverpool
  Merseyside
  L7 8XP
  
• Epsom Hospital
  Dorking Road
  Epsom
  Surrey
  KT18 7EG
  
• Torbay Hospital
  Newton Road
  Torquay
  Devon
  TQ2 7AA
  
• Mile End Hospital
  Bancroft Road
  London
  Greater London
  E1 4DG
  
• Wansbeck Hospital
  Woodhorn Lane
  Ashington
  Northumberland
  NE63 9JJ
  
• Fairfield General Hospital
  Rochdale Old Road
  Bury
  Lancashire
  BL9 7TD
  
• City Hospital
  Dudley Road
  Birmingham
  West Midlands
  B18 7QH
  
• Royal Gwent Hospital
  Cardiff Road
  Newport
  Gwent
  NP20 2UB
  
• Calderdale Royal Hospital
  Salterhebble
  Halifax
  West Yorkshire
  HX3 0PW
  
• Kettering General Hospital
  Rothwell Rd
  Kettering
  Northamptonshire
  NN16 8UZ
  
• Chase Farm Hospital
  127 The Ridgeway
  Enfield
  Middlesex
  EN2 8JL
  
• Southport And Formby District General Hospital
  Town Lane
  Southport
  Merseyside
  PR8 6PN
  
• Warrington Hospital
  Lovely Lane
  Warrington
  Cheshire
  WA5 1QG
  
• Kidderminster Hospital
  Bewdley Road
  Kidderminster
  Worcestershire
  DY11 6RJ
  
• Sunderland Royal Hospital
  Kayll Road
  Sunderland
  SR4 7TP
  
• Northumbria Healthcare NHS Foundation Trust
  North Tyneside General Hospital
  rake Lane
  North Shields
  NE29 8NH
  
• Kent & Canterbury Hospital
  Ethelbert Road
  Canterbury
  Kent
  CT1 3NG
  
• Mid Essex Hospital
  Broomfield Hospital
  Chelmsford
  Essex
  CM1 7ET
  
• EDGWARE COMMUNITY HOSPITAL
  RRP23@2.16.840.1.113883.2.1.3.2.4.18.48
  
• BEDFORD HOSPITAL NORTH WING
  RC111@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Llandudno General Hospital Site
  Llandudno General Hospital
  Llandudno
  Gwynedd
  LL30 1LB
  
• Clifton Hospital
  Pershore Road
  Lytham St. Annes
  Lancashire
  FY8 1PB
  
• QUEEN'S HOSPITAL, BURTON UPON TRENT
  RJF02@2.16.840.1.113883.2.1.3.2.4.18.48
  
• William Harvey Hospital (ashford)
  Kennington Road
  willesborough
  Ashford
  Kent
  TN24 0LZ
  
• George Eliot Hospital - Acute Services
  College Street
  Nuneaton
  Warwickshire
  CV10 7DJ
  
• SOLIHULL HOSPITAL
  RR109@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Withybush General Hospital
  Fishguard Road
  Haverfordwest
  Dyfed
  SA61 2PZ
  
• RHEUMATOLOGY SERVICE
  RW5QR@2.16.840.1.113883.2.1.3.2.4.18.48
  
• University Hospital Lewisham
  Lewisham High Street
  London
  Greater London
  SE13 6LH
  
• Ealing Hospital
  Uxbridge Road
  Southall
  Middlesex
  UB1 3HW
  
• Cossham Hospital
  Lodge Road
  Bristol
  Avon
  BS15 1LF
  
• King's Mill Hospital
  Mansfield Road
  Sutton-in-ashfield
  Nottinghamshire
  NG17 4JL
  
• Newark Hospital
  Boundary Road
  Newark
  Nottinghamshire
  NG24 4DE
  
• Shropshire Community Health NHS Trust Hq
  William Farr House
  mytton Oak Road
  Shrewsbury
  Shropshire
  SY3 8XL
  
• St Helens Hospital
  Marshalls Cross Road
  St. Helens
  Merseyside
  WA9 3DA
  
• HAYWOOD HOSPITAL
  R1E56@2.16.840.1.113883.2.1.3.2.4.18.48
  
• CHRISTCHURCH HOSPITAL
  RDZ05@2.16.840.1.113883.2.1.3.2.4.18.48
  
• Cannock Chase Hospital
  Brunswick Road
  Cannock
  Staffordshire
  WS11 5XY
  
• Halton Hospital Nightingale Building
  Halton
  Runcorn
  Cheshire
  WA7 2DA
  
• Warrington And Halton Teaching Hospitals NHS Foundation Trust
  Warrington Hospital
  lovely Lane
  Warrington
  WA5 1QG
  
• St Albans City Hospital
  Waverley Road
  St. Albans
  Hertfordshire
  AL3 5PN
  
• Hemel Hempstead Hospital
  Hillfield Road
  Hemel Hempstead
  Hertfordshire
  HP2 4AD
  
• Blackpool Victoria Hospital
  Whinney Heys Road
  Blackpool
  Lancashire
  FY3 8NR
  
• Broadgreen Hospital
  Thomas Drive
  Liverpool
  L14 3LB
  

Dr Kath Watson
biologics.register@manchester.ac.uk

Prof Kimme Hyrich
kimme.hyrich@manchester.ac.uk

More information about this study, what is involved and how to take part can be found on the study website.

The study is sponsored by University of Manchester and funded by British Society for Rheumatology (BSR) .