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Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Natasha Corballis, MBBS, MRCP (UK), MSc 01603286286
natasha.corballis@nnuh.nhs.uk


Study Location:

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Be Part of Research - Trial Details - Coronary Bifurcations With Ischaemia and Flow Assessment

Coronary Bifurcations With Ischaemia and Flow Assessment

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Coronary Bifurcation Lesions


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The coronary arteries are blood vessels that provide oxygen rich blood to the muscle of the heart. If these vessels become narrowed or blocked, this can lead to chest pain (called angina) or heart attacks. Narrowings are usually treated using metal scaffolds called drug eluting stents. However, in one in five cases where the narrowing occurs at a branching point, treating it with stents is more challenging and can cause complications. A possible alternative treatment is using a special type of balloon called a drug-coated balloon. This balloon is inflated in the blood vessel and releases medicine to help widen the blood vessel and the procedure is completed without leaving any metallic scaffold behind.

This study aims to compare drug coated balloons with drug eluting stents to see which treatment works better for narrowing that occurs at branching points. We will used advanced imaging techniques to create computer models of blood flow in the vessels, and we will follow up with patients over tie to see how well the treatments work.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Oct 2023 Jun 2026

OBSERVATIONAL

Intervention Type : DIAGNOSTIC_TEST
Intervention Description : OCT and pressure wire of the main vessel and side branch of the bifurcation are undertaken prior to and after treating the lesion and at 3-9 month follow up.

Intervention Arm Group : Drug coated balloon;Drug eluted stent;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Norwich Medical School, University of East Anglia
    Norwich
    Norfolk
    NR47TJ

Natasha Corballis, MBBS, MRCP (UK), MSc 01603286286
natasha.corballis@nnuh.nhs.uk



The study is sponsored by University of East Anglia and is in collaboration with Norfolk and Norwich University Hospitals NHS Foundation Trust.




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Read full details for Trial ID: NCT06971718
Last updated 06 May 2025

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