Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Matthew Harding
ppip@psych.ox.ac.uk


Ms Ksenija Yeeles
ppip@psych.ox.ac.uk


Dr Belinda Lennox
belinda.lennox@psych.ox.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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English | Cymraeg
Be Part of Research - Trial Details - PPiP2

PPiP2

Medical Conditions

Schizophrenia, schizotypal and delusional disorders


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The PPiP study aims to understand if some cases of psychosis are caused by immune system problems in some people.


The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause diseases called ‘autoimmune’ diseases. We can diagnose some of these autoimmune diseases using blood tests. We are specifically interested in antibodies affecting the N-methyl D-aspartate receptors (NMDA-r) or other neuronal membrane targets that may be the cause symptoms of psychosis and possibly cause some cases of schizophrenia. We are working with Early Intervention in Psychosis (EIP) services across England to estimate the prevalence of these autoimmune diseases in people with first episode psychosis.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Jan 2015 31 Mar 2027

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


Any other neurological disorders including multiple sclerosis, epilepsy, cerebrovascular disease, hydrocephalus, traumatic brain injury, meningo-encephalitis, systemic lupus erythematosus, CNS vasculitis. Primary drug induced psychosis.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Stobhill Hospital
    Glasgow
    G21 3UW
  • Lantern Centre
    Preston
    Lancashire
    PR2 8DW
  • Gloucestershire Health And Care NHS Foundation Trust
    Gloucester
    GL3 4AW
  • Berkshire Healthcare NHS Foundation Trust
    Bracknell
    RG12 1BQ
  • Cheshire And Wirral Partnership NHS Foundation Trust
    Chester
    CH2 1BQ
  • Devon Partnership NHS Trust
    Exeter
    EX2 5AF
  • Kent And Medway NHS And Social Care Partnership Trust
    Maidstone
    ME16 9PH
  • Mersey Care NHS Foundation Trust
    Prescot
    L34 1PJ
  • Northamptonshire Healthcare NHS Foundation Trust
    Kettering
    NN15 7PW
  • Rotherham Doncaster And South Humber NHS Foundation Trust
    Doncaster
    DN4 8QN
  • Southern Health NHS Foundation Trust
    Southampton
    SO40 2RZ
  • Edgware Hospital (beh-mht Services)
    Edgware
    Middlesex
    HA8 0AD
  • Science And Technology Centre
    Reading
    Berkshire
    RG6 6BZ
  • Penn Hospital
    Wolverhampton
    West Midlands
    WV4 5HN
  • Lynfield Mount Hospital
    Bradford
    West Yorkshire
    BD9 6DP
  • Fulbourn Hospital
    Cambridge
    Cambridgeshire
    CB21 5EF
  • St Pancras Hospital
    London
    Greater London
    NW1 0PE
  • Trengweath
    Redruth
    Cornwall
    TR15 2SP
  • East London NHS Foundation Trust
    London
    Greater London
    E1 8DE
  • Hertfordshire Partnership University NHS Foundation Trust
    Hatfield
    AL10 8YE
  • Norfolk And Suffolk NHS Foundation Trust
    Norwich
    Norfolk
    NR6 5BE
  • Goodmayes Hospital - Trust Headquarters
    Ilford
    Essex
    IG3 8XJ
  • Warneford Hospital
    Oxford
    Oxfordshire
    OX3 7JX
  • Somerset Partnership NHS And Social Care Trust Hq
    Bridgwater
    Somerset
    TA6 4RN
  • Maudsley Hospital
    London
    Greater London
    SE5 8AZ
  • St Margaret's Hospital
    Epping
    Essex
    CM16 6TN
  • Wonford House
    Exeter
    Devon
    EX2 5AF
  • West London NHS Trust
    Southall
    UB2 4SD
  • Upton Lea Resource Centre
    Chester
    Cheshire
    CH2 1BQ
  • Ashworth Hospital
    Liverpool
    Merseyside
    L31 1HW
  • Central And North West London NHS Foundation Trust
    London
    NW1 3AX
  • Springfield University Hospital
    London
    Greater London
    SW17 7DJ
  • Folly Hall
    Huddersfield
    West Yorkshire
    HD1 3LT
  • St Mary's Health Campus
    Portsmouth
    Hampshire
    PO3 6AD
  • FORWARD THINKING BIRMINGHAM
  • Hallam Street Hospital
    West Bromwich
    West Midlands
    B71 4NH
  • Edward Street Hospital
    West Bromwich
    West Midlands
    B70 8NL
  • Pond Lane
    Wolverhampton
    West Midlands
    WV2 1HG
  • The Cavell Centre
    Peterborough
    Cambridgeshire
    PE3 9GZ
  • Kingsway Hospital (headquarters)
    Derby
    Derbyshire
    DE22 3LZ
  • Forston Clinic
    Dorchester
    Dorset
    DT2 9TB
  • Boscombe Community Hospital
    Bournemouth
    Dorset
    BH1 4JQ
  • Nightingale House
    Bournemouth
    Dorset
    BH4 8EW
  • Bournemouth Hospital
    Bournemouth
    Dorset
    BH7 7DW
  • BOLTON EARLY INTERVENTION TEAM
  • Salford Early Intervention Team
    Salford
    Greater Manchester
    M6 5EJ
  • TRAFFORD EARLY INTERVENTION SERVICE
  • MANCHESTER EARLY INTERVENTION - NORTH TEAM
  • MANCHESTER EARLY INTERVENTION - SOUTH TEAM
  • Gervas House
    Lincoln
    Lincolnshire
    LN1 1EJ
  • University Of Oxford
    Oxford
    Oxfordshire
    OX1 2JD
  • Wedgewood Unit Mh Services
    Bury St. Edmunds
    Suffolk
    IP33 2QZ
  • Hellesdon Hospital
    Norwich
    Norfolk
    NR6 5BE
  • Marlow House
    Nottingham
    Nottinghamshire
    NG6 0DH
  • The Priory Clinic Nottingham
    Nottingham
    Nottinghamshire
    NG3 5GS
  • Highbury Hospital
    Nottingham
    Nottinghamshire
    NG6 9DR
  • Hopewood
    Nottingham
    Nottinghamshire
    NG5 3FL
  • Stonebridge Centre
    Nottingham
    Nottinghamshire
    NG3 2FH
  • Thorneywood Mount Site 2
    Nottingham
    Nottinghamshire
    NG3 2PY
  • Pennine Care NHS Foundation Trust
    Ashton-under-lyne
    OL6 7SR
  • Astley St Villa
    Dukinfield
    Cheshire
    SK16 4PU
  • Councillor Lane Resource Centre
    Cheadle
    Cheshire
    SK8 2JF
  • Tameside Hospital Mental Health Services
    Ashton-under-lyne
    Lancashire
    OL6 9RW
  • Royal Oldham Hospital Mental Health Services
    Oldham
    Lancashire
    OL1 2PN
  • Birch Hill Hospital Mental Health Services
    Rochdale
    Lancashire
    OL12 9QB
  • DONCASTER EARLY INTERVENTION
  • Wakefield Hub
    Wakefield
    West Yorkshire
    WF1 2TE
  • Kendray Hospital
    Barnsley
    South Yorkshire
    S70 3RD
  • Laura Mitchell Health Centre
    Halifax
    West Yorkshire
    HX1 1YR
  • Tatchbury Mount
    Southampton
    Hampshire
    SO40 2RZ
  • Cannon House
    Southampton
    Hampshire
    SO15 5PQ
  • Andover Community Mental Health Team
    Andover
    Hampshire
    SP10 3QX
  • Ravenswood House
    Fareham
    Hampshire
    PO17 5NA
  • Bridge Centre
    Basingstoke
    Hampshire
    RG21 7PJ
  • Melbury Lodge
    Winchester
    Hampshire
    SO22 5DL
  • Elmleigh
    Havant
    Hampshire
    PO9 2JJ
  • ANTELOPE HOUSE
  • Anchor House
    Southampton
    Hampshire
    SO40 8DX
  • Parklands Hospital
    Basingstoke
    Hampshire
    RG24 9RH
  • Petersfield Hospital
    Petersfield
    Hampshire
    GU32 3LB
  • Queen Alexandra
    Portsmouth
    PO6 3LY
  • Forest Lodge
    Southampton
    Hampshire
    SO15 2JX
  • College Keep
    Southampton
    Hampshire
    SO14 3DT
  • Bitterne Park Clinic
    Southampton
    Hampshire
    SO18 1HZ
  • Hollybank
    Havant
    PO9 2AW
  • The Parkway Centre
    Havant
    Hampshire
    PO9 1HH
  • Tees, Esk And Wear Valleys NHS Foundation Trust
    Darlington
    DL2 2TS
  • Northgate Hospital
    Great Yarmouth
    Norfolk
    NR30 1BU
  • Chatterton House
    King's Lynn
    Norfolk
    PE30 5PD
  • St Ann's Hospital
    Poole
    Dorset
    BH13 7LN
  • LADYWELL UNIT
  • Irwell Unit - Fairfield General Hospital
    Bury
    Lancashire
    BL9 7TD
  • Woodlands Mh Services
    Ipswich
    Suffolk
    IP4 5PD
  • ST PANCRAS HOSPITAL
  • Carlton Court
    Lowestoft
    Suffolk
    NR33 8AG
  • St Mary's Community Healthcare
    Portsmouth
    PO3 6AD
  • BETHLEM ROYAL HOSPITAL
  • THE LAMBETH HOSPITAL

Matthew Harding
ppip@psych.ox.ac.uk


Ms Ksenija Yeeles
ppip@psych.ox.ac.uk


Dr Belinda Lennox
belinda.lennox@psych.ox.ac.uk



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by University of Oxford and funded by Medical Research Council (MRC) .




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for Trial ID: CPMS 18451

Last updated 30 May 2025

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