Ask to take part

Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.

Contact Information:

Dr George Mells
add-tr.ukpbc@nhs.net


Dr Richard Sandford
rns13@cam.ac.uk


More information about this study, what is involved and how to take part can be found on the study website.

Study Location:

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English | Cymraeg
Be Part of Research - Trial Details - PBC Genetics Study

PBC Genetics Study

Medical Conditions

Diseases of liver


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


The PBC Genetics Study is a national effort to establish a PBC DNA collection consisting of DNA samples from approximately 5000 patients with PBC. The DNA collection has already been used for a genome-wide association study (GWAS) of PBC. The next major analysis will be a genome wide association study of response to Ursodeoxycholic acid (UDCA).

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

06 Dec 2007 31 Dec 2028

Observational

Observational type: Not Specified;



You can take part if:



You may not be able to take part if:


Child or unable to provide informed consent.


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • Princess Of Wales Hospital
    Bridgend
    Mid Glamorgan
    CF31 1RQ
  • Airedale General Hospital
    Keighley
    West Yorkshire
    BD20 6TD
  • Bradford Royal Infirmary
    Bradford
    West Yorkshire
    BD9 6RJ
  • Chesterfield Royal Hospital
    Chesterfield
    Derbyshire
    S44 5BL
  • Ipswich Hospital
    Ipswich
    Suffolk
    IP4 5PD
  • Guy's Hospital
    London
    Greater London
    SE1 9RT
  • Harrogate District Hospital
    Harrogate
    North Yorkshire
    HG2 7SX
  • Homerton University Hospital
    London
    Greater London
    E9 6SR
  • Castle Hill Hospital
    Cottingham
    North Humberside
    HU16 5JQ
  • King's College Hospital (denmark Hill)
    London
    Greater London
    SE5 9RS
  • Kingston Hospital
    Kingston Upon Thames
    Surrey
    KT2 7QB
  • Luton & Dunstable Hospital
    Luton
    Bedfordshire
    LU4 0DZ
  • Pinderfields General Hospital
    Wakefield
    West Yorkshire
    WF1 4DG
  • Milton Keynes Hospital
    Milton Keynes
    Buckinghamshire
    MK6 5LD
  • Norfolk & Norwich University Hospital
    Norwich
    Norfolk
    NR4 7UY
  • Diana, Princess Of Wales Hospital
    Grimsby
    South Humberside
    DN33 2BA
  • Derriford Hospital
    Plymouth
    Devon
    PL6 8DH
  • Royal Berkshire Hospital
    Reading
    Berkshire
    RG1 5AN
  • Royal Cornwall Hospital (treliske)
    Truro
    Cornwall
    TR1 3LJ
  • Royal Devon & Exeter Hospital (wonford)
    Exeter
    Devon
    EX2 5DW
  • North Devon District Hospital
    Barnstaple
    Devon
    EX31 4JB
  • Royal Free Hospital
    London
    Greater London
    NW3 2QG
  • Musgrove Park Hospital
    Taunton
    TA1 5DA
  • Greenfields Day Centre
    Bridgwater
    Somerset
    TA6 3RT
  • Warwick Hospital
    Warwick
    Warwickshire
    CV34 5BW
  • St George's Hospital (tooting)
    London
    Greater London
    SW17 0QT
  • Russells Hall Hospital
    Dudley
    West Midlands
    DY1 2HQ
  • Freeman Hospital
    Newcastle Upon Tyne
    Tyne And Wear
    NE7 7DN
  • Royal Bournemouth General Hospital
    Bournemouth
    Dorset
    BH7 7DW
  • New Cross Hospital
    Wolverhampton
    West Midlands
    WV10 0QP
  • Weston General Hospital
    Weston-super-mare
    Avon
    BS23 4TQ
  • Leicester General Hospital
    Leicester
    Leicestershire
    LE5 4PW
  • Royal Lancaster Infirmary
    Lancaster
    Lancashire
    LA1 4RP
  • Arrowe Park Hospital
    Wirral
    Merseyside
    CH49 5PE
  • Alexandra Hospital
    Redditch
    Worcestershire
    B98 7UB
  • Worcestershire Royal Hospital
    Worcester
    Worcestershire
    WR5 1DD
  • Hereford County Hospital
    Hereford
    Herefordshire
    HR1 2ER
  • Yeovil District Hospital
    Yeovil
    Somerset
    BA21 4AT
  • Barnsley Hospital
    Barnsley
    South Yorkshire
    S75 2EP
  • Barnet Hospital
    Barnet
    Hertfordshire
    EN5 3DJ
  • Queen Elizabeth Hospital
    Birmingham
    West Midlands
    B15 2TH
  • Leicester Royal Infirmary
    Leicester
    Leicestershire
    LE1 5WW
  • University Hospital Aintree
    Liverpool
    Merseyside
    L9 7AL
  • Musgrove Park Hospital
    Taunton
    Somerset
    TA1 5DA
  • Southampton General Hospital
    Southampton
    Hampshire
    SO16 6YD
  • Addenbrooke's Hospital
    Cambridge
    Cambridgeshire
    CB2 0QQ
  • St Mary's Hospital (hq)
    London
    Greater London
    W2 1NY
  • Nottingham University Hospitals NHS Trust - Queen's Medical Centre Campus
    Nottingham
    Nottinghamshire
    NG7 2UH
  • John Radcliffe Hospital
    Oxford
    Oxfordshire
    OX3 9DU
  • Stoke Mandeville Hospital
    Aylesbury
    Buckinghamshire
    HP21 8AL
  • Cwm Taf Morgannwg University Local Health Board
    Pontypridd
    Mid Glamorgan
    CF37 1LB
  • Royal Derby Hospital
    Derby
    Derbyshire
    DE22 3NE
  • Frimley Park Hospital
    Frimley
    Surrey
    GU16 7UJ
  • Queen Elizabeth Hospital
    Gateshead
    Tyne And Wear
    NE9 6SX
  • Basingstoke And North Hampshire Hospital
    Basingstoke
    Hampshire
    RG24 9NA
  • Royal Hampshire County Hospital
    Winchester
    Hampshire
    SO22 5DG
  • Hull Royal Infirmary
    Hull
    North Humberside
    HU3 2JZ
  • Basildon Hospital
    Basildon
    Essex
    SS16 5NL
  • The James Cook University Hospital
    Middlesbrough
    Cleveland
    TS4 3BW
  • Queen Alexandra Hospital
    Portsmouth
    Hampshire
    PO6 3LY
  • Royal Hallamshire Hospital
    Sheffield
    South Yorkshire
    S10 2JF
  • Royal Liverpool University Hospital
    Liverpool
    Merseyside
    L7 8XP
  • Wycombe Hospital
    High Wycombe
    Buckinghamshire
    HP11 2TT
  • Royal Bournemouth Hospital
    Bournemouth
    BH7 7DW
  • Gloucestershire Royal Hospital
    Gloucester
    Gloucestershire
    GL1 3NN
  • Royal Gwent Hospital
    Newport
    Gwent
    NP20 2UB
  • St Peter's Hospital
    Chertsey
    Surrey
    KT16 0PZ
  • Amersham Hospital
    Amersham
    Buckinghamshire
    HP7 0JD
  • Calderdale Royal Hospital
    Halifax
    West Yorkshire
    HX3 0PW
  • The Royal Glamorgan Hospital
    Pontyclun
    Mid Glamorgan
    CF72 8XR
  • Prince Charles Hospital Site
    Merthyr Tydfil
    Mid Glamorgan
    CF47 9DT
  • James Paget University Hospital
    Great Yarmouth
    Norfolk
    NR31 6LA
  • Kettering General Hospital
    Kettering
    Northamptonshire
    NN16 8UZ
  • Chase Farm Hospital
    Enfield
    Middlesex
    EN2 8JL
  • Southport General Infirmary
    Southport
    Merseyside
    PR8 6PH
  • Whiston Hospital
    Prescot
    Merseyside
    L35 5DR
  • East Surrey Hospital
    Redhill
    Surrey
    RH1 5RH
  • Warrington Hospital
    Warrington
    Cheshire
    WA5 1QG
  • St Richard's Hospital
    Chichester
    West Sussex
    PO19 6SE
  • Kidderminster Hospital
    Kidderminster
    Worcestershire
    DY11 6RJ
  • Sunderland Royal Hospital
    Sunderland
    SR4 7TP
  • South Tyneside District Hospital
    South Shields
    NE34 0PL
  • Darent Valley Hospital
    Dartford
    Kent
    DA2 8DA
  • University Hospital Of North Tees
    Stockton-on-tees
    Cleveland
    TS19 8PE
  • Northern General Hospital
    Sheffield
    South Yorkshire
    S5 7AU
  • Kent & Canterbury Hospital
    Canterbury
    Kent
    CT1 3NG
  • University Hospital Of Hartlepool
    Hartlepool
    Cleveland
    TS24 9AH
  • Conquest Hospital
    St. Leonards-on-sea
    East Sussex
    TN37 7RD
  • Royal Surrey County Hospital
    Guildford
    Surrey
    GU2 7XX
  • Eastbourne District General Hospital
    Eastbourne
    East Sussex
    BN21 2UD
  • St James's University Hospital
    Leeds
    West Yorkshire
    LS9 7TF
  • Yeovil District Hospital
    Yeovil
    BA21 4AT

Dr Richard Sandford
rns13@cam.ac.uk


Dr George Mells
add-tr.ukpbc@nhs.net



More information about this study, what is involved and how to take part can be found on the study website.


The study is sponsored by CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST and funded by Medical Research Council (MRC); PBC Foundation (UK) Limited; THE ADDENBROOKE'S CHARITABLE TRUST; University of Cambridge; Wellcome Trust; .




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for Trial ID: CPMS 5630

Last updated 08 April 2026

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