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Contact Information:

BioNTech clinical trials patient information +49 6131 9084
patients@biontech.de


Study Location:

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Be Part of Research - Trial Details - Safety and Preliminary Efficacy Trial of BNT142 in Patients with CLDN6-positive Solid Tumors

Safety and Preliminary Efficacy Trial of BNT142 in Patients with CLDN6-positive Solid Tumors

Recruiting

Open to: ALL

Age: 18.0 - N/A

Medical Conditions

Neoplasms


This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.


This study is an open-label, multicenter, Phase I/IIa, dose escalation, safety, and pharmacokinetics (PK) study of BNT142 followed by expansion cohorts in patients with Claudin 6 (CLDN6)-positive advanced tumors.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

Mar 2022 Oct 2025

INTERVENTIONAL

Intervention Type : BIOLOGICAL
Intervention Description : Intravenous bolus/infusion

Intervention Arm Group : BNT142;



You can take part if:



You may not be able to take part if:


This is in the inclusion criteria above


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • The Clatterbridge Cancer Centre NHS Foundation Trust
    Liverpool
    L7 8YA
  • Nottingham University Hospitals NHS Trust - Nottingham City Hospital
    Nottingham
    NG5 1PB
  • Guy'S Hospital - Guy'S & St Thomas' Nhs Foundation Trust
    London
    SE1 9RT
  • Hammersmith Hospital, Imperial College School Of Medicine - Imperial College Healthcare NHS Trust
    London
    W12 0HS
  • Sarah Cannon Research Institute (Recruiting only for Part 2)
    London
    W1G 6AD
  • Churchill Hospital - Oxford University Hospitals NHS Foundation Trust
    Oxford
    OX3 7LE
  • Cambridge University Hospitals NHS Foundation Trust
    Cambridge
    CB2 0QQ

BioNTech clinical trials patient information +49 6131 9084
patients@biontech.de



The study is sponsored by BioNTech SE




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Read full details for Trial ID: NCT05262530
Last updated 30 January 2025

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