We'd like your feedback
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Contact the study team using the details below to take part. If there are no contact details below please ask your doctor in the first instance.
Dr
Marie-Hélène
Boudrias
m.boudrias@ion.ucl.ac.uk
Miss
Ella
Clark
e.clark@ucl.ac.uk
Dr
Nick
Ward
n.ward@ucl.ac.uk
This information is provided directly by researchers, and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information. In some summaries, you may come across links to external websites. These websites will have more information to help you better understand the study.
Motor impairment after stroke is common following damage to areas of the brain normally involved in planning and executing motor commands. Damage may involve cortex, subcortical regions, or both, leading to disconnection of cortical motor regions from one another or from lower brain stem centres and spinal cord motor neurons. Regeneration of damaged tissue in adults is limited. Treatment induced improvement in motor function is therefore likely to be a consequence of reorganisation of the interactions between surviving elements of the motor network. It is vitally important therefore to develop tools which will allow us to investigate changes in connectivity between brain regions after stroke. Brain reorganization has previously been described in terms of regional changes in task related activity. This project will investigate the causal influences of motor areas on one another using functional brain imaging. Specifically, it will investigate how these connections are modulated by anatomical damage and time after stroke in a way that influences recovered function.
Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.
The recruitment start and end dates are as follows:
Observational type: Clinical Laboratory Study;
You can take part if:
You may not be able to take part if:
Exclusion criteria are:(1) language/cognitive deficits sufficient to give properly informed consent and to impair cooperation in the study; (3) inability to perform the motor task due to complete paralysis of hand grip; (4) metal implants.
Below are the locations for where you can take part in the trial. Please note that not all sites may be open.
Dr
Marie-Hélène
Boudrias
m.boudrias@ion.ucl.ac.uk
Miss
Ella
Clark
e.clark@ucl.ac.uk
Dr
Nick
Ward
n.ward@ucl.ac.uk
The study is sponsored by University College London and funded by Wellcome Trust .
Your feedback is important to us. It will help us improve the quality of the study information on this site. Please answer both questions.
Read full details
for Trial ID: CPMS 8540
You can print or share the study information with your GP/healthcare provider or contact the research team directly.
