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Contact Information:

Miss Lynsey Spillman
Lynsey.spillman@mrc-epid.cam.ac.uk


Prof Simon Griffin
ProfGP@medschl.cam.ac.uk


Study Location:

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Be Part of Research - Trial Details - The BOLT Study: Behaviours and outcomes after liver transplant v1

The BOLT Study: Behaviours and outcomes after liver transplant v1

Completed

Open to: Female / Male

Age: 18 Years - N/A

Medical Conditions

Diseases of liver
Persons with potential health hazards related to family and personal history and certain conditions influencing health status


This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


It is common for people to develop cardiovascular disease, obesity, diabetes, raised cholesterol and high blood pressure after a liver transplant. This increases the risk of poor health and lowers quality of life. A healthy diet and physical activity are important to enable people to stay healthy after transplant. We don’t know whether people have a healthy diet and are physically active after a transplant or not, or what influences these behaviours. This may be different to the general public due to the effects of liver disease, the transplant operation and medication.

This research aims to find out, for liver transplant recipients:
1. What are their diet and physical activity behaviours?
2. What are the factors influencing these behaviours?
3. Are diet and physical activity behaviours associated with cardiovascular disease risk factors and quality of life?

Knowing the answers to these questions will help to improve post-transplant care.

What will this research involve?

Part 1:
We will invite patients who have a liver transplant at Cambridge University Hospitals NHS Foundation Trust to participate when they are 4-5 months post-transplant. At 6 and 12 months after transplant we will measure quality of life, diet, physical activity and things that might influence diet and activity. We will collect information on risk factors for cardiovascular disease, such as blood pressure and cholesterol levels. With this information we will look at the links between diet, activity, cardiovascular disease risk factors, quality of life and the reasons for diet and activity behaviours.

Part 2:
We will invite some participants from part 1 of the study to interviews to explore the things influencing their diet and activity in more depth. We will choose people who have a range of diet and activity behaviours, so that a range of experiences are explored.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

06 Jan 2020 26 May 2021

Observational

Observational type: Cohort study;



You can take part if:



You may not be able to take part if:


• Non-English speaking • Any additional solid organ transplant other than liver +/- kidney e.g. pancreas or multivisceral transplant. • Unable to provide informed consent


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

Miss Lynsey Spillman
Lynsey.spillman@mrc-epid.cam.ac.uk


Prof Simon Griffin
ProfGP@medschl.cam.ac.uk



The study is sponsored by CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST and funded by NIHR Academy .




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for Trial ID: CPMS 43664

Last updated 22 October 2021

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